A three-dimensional “turn-on” sensor array for simultaneous discrimination of multiple heavy metal ions based on bovine serum albumin hybridized fluorescent gold nanoclusters

Development status of novel spectral imaging techniques and application to traditional Chinese medicine

“…Xi et al. [ 19 ] designed a gold nanocluster fluorescent probe encapsulated in bovine serum albumin to detect heavy ions in blood. Three different concentrations of dopamine were used as nonspecific receptors to quench the fluorescent probe by forming polydopamine.…”

“…Heavy metal ions prevented fluorescence quenching by interfering with the formation of polydopamine. Therefore, heavy metals can be conveniently detected using fluorescent probes that react with heavy metal ions [ 19 ]. Accordingly, fluorescence spectral imaging is a potential approach for the direct and rapid quantitative detection of pathological changes in diseases.…”

Gold Nanoclusters and Silica-Coated Carbon Dots-Assisted Ratiometric Fluorescent Nanosensors for Ultrasensitive Detection of Glyphosate

“…25,26 Of them, gold nanoclusters (AuNCs) with outstanding merits of large Stokes shift, good biocompatibility, strong photoluminescence responses, fascinating optical stability, and low toxicity have popularized as promising fluorescent nanolabels for biosensing. 27 More interestingly, the fluorescence of bovine serum albuminstabilized AuNCs (BSA-AuNCs) can be quenched by copper ion (Cu 2+ ) due to the coordinate interaction between Cu 2+ and BSA, which enables BSA-AuNCs to serve as the ideal fluorescent signal probes. 28 In addition, nitrogen-doped carbon dots (N-CDs) with excellent optical properties, simple synthesis, good biosafety, environmental friendliness, robust photostability, low photobleaching, and tunable fluorescence emission, have drawn worldwide attention as the nextgeneration green fluorescent nanomaterials to replace conventionally used fluorophores in the sensing fields.…”

“…Regarding the above considerations, diverse fluorescent labels are explored to develop the ratiometric platforms for glyphosate detection. , Of them, gold nanoclusters (AuNCs) with outstanding merits of large Stokes shift, good biocompatibility, strong photoluminescence responses, fascinating optical stability, and low toxicity have popularized as promising fluorescent nanolabels for biosensing . More interestingly, the fluorescence of bovine serum albumin-stabilized AuNCs (BSA-AuNCs) can be quenched by copper ion (Cu 2+ ) due to the coordinate interaction between Cu 2+ and BSA, which enables BSA-AuNCs to serve as the ideal fluorescent signal probes .…”

Interfacial Self-Assembly of Surfactant-Free Au Nanoparticles as a Clean Surface-Enhanced Raman Scattering Substrate for Quantitative Detection of As5+ in Combination with Convolutional Neural Networks

“…Heavy metals are widely employed in industry and agriculture as a result of their excellent physical and chemical properties. − Heavy metal ions are easily enriched into living organisms through the food chain in the ecological cycle because of their non-degradability, thus seriously harming plants, animals, and humans. − The traditional detection methods are divided into three main categories, including spectroscopy, chromatography, and electrochemical analysis . However, these methods require multiple sample pre-concentration processes and expensive instruments that fail to meet the requirements of flexible operations in actual measurements.…”