A Tibetan adolescent girl suffered frostbite on the journey of pilgrimage: A case report

Xiao, Yue; Hao, Dan; Yue, Xin; Jiang, Xian

doi:10.1016/j.cjtee.2021.10.006

Cited by 2 publications

(2 citation statements)

References 7 publications

(13 reference statements)

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“…However, in recent years, it has impacted individuals living in cold environments in peaceful areas[ 1 ]. In China, people residing in temperate plains rarely experience frostbites[ 5 , 8 ]. Consequently, many hospitals, including the one mentioned in this report, lack established frostbite treatment protocols and experience, resulting in treatment delays for patients.…”

Section: Discussionmentioning

confidence: 99%

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Comprehensive treatment of deep frostbite of multiple fingers after trauma: A case report

Wang,

Li,

Cheng

et al. 2023

World J Clin Cases

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BACKGROUND Frostbite is becoming increasingly common in urban environments, and severe cases can lead to tissue loss. The treatment goal is to preserve tissue and function; the sooner appropriate treatment is administered, the more tissue can be saved. However, not every patient with deep frostbite seeks medical care promptly. CASE SUMMARY We report the case of a 73-year-old male patient who was lost in the wilderness for 2 d due to trauma and confusion. He experienced deep frostbite on multiple fingers. Treatment should not be discontinued for patients with deep frostbite who present after the optimum treatment timing. Bullae that no longer form (bloody) blisters within 24 h of aspiration should be removed. Mucopolysaccharide polysulfate cream has clinical value in frostbite treatment. The patient was transferred to Chinese Academy of Medical Sciences and Peking Union Medical College Hospital 12 h after being rescued. The patient had contraindications for thrombolysis, the most effective treatment, due to intracranial hemorrhage and presenting past the optimum treatment timing. We devised a comprehensive treatment plan, which involved delayed use vasodilators and high-pressure oxygen therapy at day 49 post-injury. We experimented with mucopolysaccharide polysulfate cream to treat the frostbite. The aim of the treatment was to safeguard as much tissue as possible. In the end, the fingers that suffered from frostbite were able to be partially preserved. CONCLUSION The case indicated that patients with severe frostbite who missed the optimal treatment time and had contraindications for thrombolysis could still partially preserve the affected limbs through comprehensive treatment.

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Section: Discussionmentioning

confidence: 99%

“…For deep frostbite, the treatment aims to reduce the area of the limb affected and improve limb function as much as possible. Studies have shown that most deep frostbite cases result in amputation[ 6 - 8 ]. Thrombolytic therapy within 24 h of frostbite can significantly reduce tissue damage[ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Comprehensive treatment of deep frostbite of multiple fingers after trauma: A case report

Wang,

Li,

Cheng

et al. 2023

World J Clin Cases

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Frostbite treatment: a systematic review with meta-analyses

Regli,

Oberhammer,

Zafren

et al. 2023

Scand J Trauma Resusc Emerg Med

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Introduction Our objective was to perform a systematic review of the outcomes of various frostbite treatments to determine which treatments are effective. We also planned to perform meta-analyses of the outcomes of individual treatments for which suitable data were available. Main Body We performed a systematic review and meta-analyses in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. We searched PubMed, Cochrane Trials, and EMBase to identify primary references from January 1, 1900, to June 18, 2022. After eliminating duplicates, we screened abstracts to identify eligible studies containing information on treatment and outcomes of Grade 2 to 4 frostbite. We performed meta-analyses of groups of articles that provided sufficient data. We registered our review in the prospective registry of systematic reviews PROSPERO (Nr. 293,693). We identified 4,835 potentially relevant studies. We excluded 4,610 studies after abstract screening. We evaluated the full text of the remaining 225 studies, excluding 154. Ultimately, we included 71 articles with 978 cases of frostbite originating from 1 randomized controlled trial, 20 cohort studies and 51 case reports. We found wide variations in classifications of treatments and outcomes. The two meta-analyses we performed both found that patients treated with thrombolytics within 24 h had better outcomes than patients treated with other modalities. The one randomized controlled trial found that the prostacyclin analog iloprost was beneficial in severe frostbite if administered within 48 h. Conclusions Iloprost and thrombolysis may be beneficial for treating frostbite. The effectiveness of other commonly used treatments has not been validated. More prospective data from clinical trials or an international registry may help to inform optimal treatment.

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A Tibetan adolescent girl suffered frostbite on the journey of pilgrimage: A case report

Cited by 2 publications

References 7 publications

Comprehensive treatment of deep frostbite of multiple fingers after trauma: A case report

Comprehensive treatment of deep frostbite of multiple fingers after trauma: A case report

Frostbite treatment: a systematic review with meta-analyses

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