“…Perhaps the most notable and thoroughly studied probe showing evidence of cosmological-scale anisotropy and a cosmological-scale axis is the cosmic microwave background (Eriksen et al, 2004;Cline et al, 2003;Gordon and Hu, 2004;Campanelli et al, 2007;Zhe et al, 2015;Abramo et al, 2006;Mariano and Perivolaropoulos, 2013;Land and Magueijo, 2005;Ade et al, 2014;Santos et al, 2015;Dong et al, 2015;Gruppuso et al, 2018;Yeung and Chu, 2022). Other messengers that show cosmological anisotropy and possible axes in the large-scale structure include radio sources (Ghosh et al, 2016;Tiwari and Jain, 2015;Tiwari and Nusser, 2016), LX-T scaling (Migkas et al, 2020), short gamma ray bursts (Mészáros, 2019), cosmological acceleration rates (Perivolaropoulos, 2014;Migkas et al, 2021;Krishnan et al, 2021), galaxy morphol-ogy types (Javanmardi and Kroupa, 2017), Ia supernova (Javanmardi et al, 2015;Lin et al, 2016), dark energy (Adhav et al, 2011;Adhav, 2011;Perivolaropoulos, 2014;Colin et al, 2019), fine structure constant (Webb et al, 2011), galaxy motion (Skeivalas et al, 2021), H o (Luongo et al, 2021), polarization of quasars (Hutsemékers et al, 2005;Secrest et al, 2021;Zhao and Xia, 2021;Semenaite et al, 2021), and high-energy cosmic rays…”