A topical gel nanoformulation of amphotericin B (AmB) for the treatment of cutaneous leishmaniasis (CL)

Boshrouyeh, Reza; Amari, Samar; Ghandashtani, Mohammad Boshrouyeh; Alavi, Seyed Ebrahim; Shahmabadi, Hasan Ebrahimi

doi:10.1007/s10971-023-06041-w

Cited by 15 publications

(1 citation statement)

References 53 publications

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“…These enhancers include compounds that promote stratum corneum hydration and chemical penetration enhancers [54]. Strategies such as complexation, microencapsulation, or inclusion into certain delivery systems may be employed to enhance the solubility, bioavailability, and skin penetration of these compounds [55][56][57][58]. Micronutrients are commonly delivered using enhancers such as gums, oral tablets, buccal sprays, creams, gels, and ointments [59,60].…”

Section: Introductionmentioning

confidence: 99%

Using a Topical Formulation of Vitamin D for the Treatment of Vitiligo: A Systematic Review

Al-Smadi,

Ali,

Alavi

et al. 2023

Cells

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Vitamin D is one significant prohormone substance in human organ systems. It is a steroidal hormone produced in the skin upon exposure to UVB rays. This paper presents a systematic review of the utilization of topical vitamin D, specifically cholecalciferol, calcipotriol, and tacalcitol, in the treatment of vitiligo. It considers the role of vitamin D in stimulating the synthesis of melanin and melanogenesis, which can help with the process of repigmentation. The inclusion of calcipotriol or tacalcitol in Narrowband Ultraviolet Phototherapy (NB-UVB) has shown the potential to enhance therapeutic outcomes for vitiligo. However, their effectiveness in combination with Psoralens Long Wave Ultraviolet Radiation (PUVA) and Monochromatic Excimer Light (MEL) treatment for vitiligo is limited. In contrast, combining topical corticosteroids with vitamin D analogues has demonstrated superior efficacy in treating vitiligo compared to using vitamin D analogues alone, while also providing the added benefit of reducing corticosteroid-related adverse effects. In addition, treating stable vitiligo with topical cholecalciferol and microneedling has shown success. Future studies are needed to ascertain an efficient method of administering vitamin D topically as an anti-vitiligo agent.

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Section: Introductionmentioning

confidence: 99%

Using a Topical Formulation of Vitamin D for the Treatment of Vitiligo: A Systematic Review

Al-Smadi,

Ali,

Alavi

et al. 2023

Cells

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Liposomes as sustainable delivery systems in food, cosmetic, and pharmaceutical applications

Luo,

Oomah,

Akoetey

et al. 2024

J Americ Oil Chem Soc

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Liposomes are artificial microscopic vesicles composed of phospholipid bilayers with the ability to encapsulate both hydrophobic and hydrophilic molecules, owing to the amphipathic nature of lipids. Hydrophobic molecules can be stored within the bilayer membrane, while hydrophilic molecules can be embedded in the inner core of liposomes. Encapsulated compounds within liposomes are protected from environmental and chemical alterations, such as enzymatic and chemical modifications, as well as changes against extreme pH, temperature, and ionic strength. Liposomes protective nature highlights their importance as nanocarriers for a wide spectrum of hydrophobic and hydrophilic molecules. This review offers a concise introduction to the fundamental physicochemical properties of liposomes and the various production methods including the role of cholesterol and potential alternatives such as phytosterols. It also provides an up‐to‐date overview of liposomes applications as delivery vehicles in food, cosmetics, and pharmaceuticals.

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Advances in Antileishmanial Chemotherapy

Shuhail,

Das,

Datta

et al. 2023

Challenges and Solutions Against Visceral Leishmaniasis

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A topical gel nanoformulation of amphotericin B (AmB) for the treatment of cutaneous leishmaniasis (CL)

Cited by 15 publications

References 53 publications

Using a Topical Formulation of Vitamin D for the Treatment of Vitiligo: A Systematic Review

Using a Topical Formulation of Vitamin D for the Treatment of Vitiligo: A Systematic Review

Liposomes as sustainable delivery systems in food, cosmetic, and pharmaceutical applications

Advances in Antileishmanial Chemotherapy

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