“…The latter could be a threshold value, required for cell survival, by preventing cells from losing K + ions, a prerequisite to enter the apoptotic pathway. 55,56 Alternatively, such values could be apt to maintain, in a properly activated state, [57][58][59] those voltage-dependent proteins involved in cell signalling, as well as to control the appropriate Ca 2+ entry into the cells through voltage-dependent channels. 60 On the whole, based on data reported in this study, we propose to include K + channel encoding genes, in particular the herg gene, among novel molecular markers of hematological disorders that are involved in the regulation of hemopoietic cell proliferation.…”