Multi-sensor information fusion is that fuses information of multiple sensors gained through use of redundant, complementary, or timelier information in a system can provide more reliable and accurate information. Under the research of mobile robot environmental information, a control method of fuzzy neural network based on T-S (Takagi-Sugeno) type is given, it can fuses effectively collected information from multiple ultrasonic sensors and a CCD camera, and realize the real-time control for mobile robot. The results on mobile robot obstacles avoidance verified the effectiveness of the method.