A trial of intra-lymphatic cyclophosphamide in patients with arm lymphoedema due to metastatic breast carcinoma

Kitchen, G.; Garrett, M.J.

doi:10.1016/s0009-9260(71)80088-0

Cited by 5 publications

(3 citation statements)

References 2 publications

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“…However, Greenspan (1961) reported cyclophosphamideinduced temporary regression in angiosarcoma which had metastasized to the lungs after failure of a Thiotepa/methotrexate combination. Nielsen (1 967) and Kitchen and Garrett (1971) reported the effectiveness of intralymphatic injection of cyclophosphamide in improving massive lymphoedema of the arm secondary to local spread of carcinoma of the breast.…”

Section: Discussionmentioning

confidence: 99%

Postmastectomy lymphangiosarcoma-temporary response to cyclophosphamide chemotherapy in 2 cases

Tong

Winter

1974

Journal of British Surgery

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Section: Discussionmentioning

confidence: 99%

Postmastectomy lymphangiosarcoma-temporary response to cyclophosphamide chemotherapy in 2 cases

Tong

Winter

1974

Journal of British Surgery

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“…Kitchen and Garrett published a series of cases describing the injection of cyclophosphamide in four patients with secondary lymphedema due to lymphatic metastasis from breast carcinoma [8]. Injections were done at an outpatient clinic, and no complications were noticed.…”

Section: Reviewmentioning

confidence: 99%

“…Injections were done at an outpatient clinic, and no complications were noticed. Two patients presented with clinical improvement in edema and symptom relief [8].…”

Section: Reviewmentioning

confidence: 99%

Pharmacotherapy Agents in Lymphedema Treatment: A Systematic Review

Forte

Boczar

Huayllani

et al. 2019

Cureus

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It is estimated that one in every six patients undergoing solid cancer treatment will develop secondary lymphedema. We conducted a systematic review of publications assessing the potential use of pharmacotherapy agents in lymphedema treatment. The search was conducted on PubMed and eligibility criteria excluded papers that investigated other therapies or focused on primary lymphedema. From 285 potential papers found in the literature, seven studies fulfilled the eligibility criteria. Different types of therapies were proposed, but all of them interfered with inflammation in the lymphedema tissue. Interestingly, the majority of publications were clinical, and three authors conducted randomized, placebo-controlled, double-blinded clinical studies. Promising results were observed for the oral administration of ketoprofen or selenium and topical tacrolimus. Pharmacotherapy agents were successfully described in lymphedema treatment in clinical and experimental studies. The benefits of delivering ketoprofen, selenium, or tacrolimus in lymphedema were noticed, and these therapies were easily delivered and well-tolerated.

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Increased lymphatic delivery of bleomycin by microsphere in oil emulsion and its effect on lymph node metastasis

Matsuru

Muranishi

Sakakibara

et al. 1979

International Journal of Pharmaceutics

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A trial of intra-lymphatic cyclophosphamide in patients with arm lymphoedema due to metastatic breast carcinoma

Cited by 5 publications

References 2 publications

Postmastectomy lymphangiosarcoma-temporary response to cyclophosphamide chemotherapy in 2 cases

Postmastectomy lymphangiosarcoma-temporary response to cyclophosphamide chemotherapy in 2 cases

Pharmacotherapy Agents in Lymphedema Treatment: A Systematic Review

Increased lymphatic delivery of bleomycin by microsphere in oil emulsion and its effect on lymph node metastasis

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