A Triterpene and a Depside from Parmotrema austrocetratum Elix and J. Johnst.

Abstract

A Triterpene and a Depside from Parmotrema austrocetratum Elix and J. Johnst. ABSTRACT Introduction: Parmotrema austrocetratum Elix and J. Johnst. (syn. Rimelia austrocetrata Elix and J. Johnst.) which belongs to a large genus of lichenized fungi, Parmotrema Massalongo under family Parmeliaceae was investigated for its chemical constituents. Methods: The compounds were isolated by silica gel chromatography and their chemical structures were elucidated by NMR spectroscopy. Results: Chemical investigation of the dichloromethane extract of Parmotrema austrocetratum Elix and J. Johnst. has led to the isolation of zeorin (1) and atranorin (2). Conclusion: P. austrocetratum shares similar chemical characteristic with other Parmotrema species which afforded atranorin. This work highlights the first reported isolation of 1 from P. austrocetratum and the genus Parmotrema. ABSTRACT SUMMARY • Chemical investigation of the dichloromethane extract of P. austrocetratum has led to the isolation of zeorin (1) and atranorin (2). This is the first report on the isolation of 1 from P. austrocetratum and the genus Parmotema.Consolacion Y. Ragasa: Full Professor 10

Chemical Constituents of Moss Macromitrium orthostichum Nees ex Schwägr.

“…Silica gel chromatography of the dichloromethane extract of Macromitrium orthostichum afforded zeorin (1), atranorin (2) and a mixture of β-sitosterol (3) and stigmasterol (4) in about 1:1 ratio. The structure of compound 1 was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by comparison of its NMR data with those reported in the literature [4]. The NMR data of compound 2 were in accordance with those reported in the literature for atranorin [4]; compound 3 for β-sitosterol [5] and compound 4 for strigmasterol [5].…”

“…The structure of compound 1 was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by comparison of its NMR data with those reported in the literature [4]. The NMR data of compound 2 were in accordance with those reported in the literature for atranorin [4]; compound 3 for β-sitosterol [5] and compound 4 for strigmasterol [5]. Although there is no reported biological activity for M. orthostichum, the compounds isolated from the plant were reported to possess diverse activities.…”

Hopane-6α,16α,22-triol: A New Hopane Triterpenoid from the Lichen Parmotrema sancti-angelii

“…15 Only zeorin ( 5 ) was formerly described in Parmotrema austrocetratum . 16 To the best of our knowledge, compounds 1 to 4 and 6 were first reported in Parmotrema genus. Moreover, the cytotoxic activities of 2 isolated compounds 2 and 4 against liver hepatocellular carcinoma (HepG2), human lung cancer (NCI-H460), and human breast cancer (MCF-7) cell lines were evaluated.…”