A Tuberculosis Screening and Chemoprophylaxis Project in Children from a High Risk Population in Edmonton, Alberta

Doering, D; Kocuipchyk, Rose; Lester, Shelley

doi:10.1007/bf03404496

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Between 2013 and 2017, 95.9% of eligible migrant students were screened within 24 months of arrival in South Australia, confirming that the programme facilitates screening during the highest-risk interval for TB reactivation. The overall positive TST rate of 17.6% is comparable with other studies assessing targeted programmes for LTB in similar settings, [17][18][19][20][21][22] and higher than a recent longitudinal study of Swiss migrant students, 23 suggesting an appropriately selected target population. The treatment completion rate of 84.3% is greater than 18,21 or comparable with 17,19 rates reported in other studies of school-age students.…”

Section: Discussionsupporting

confidence: 78%

“…The overall positive TST rate of 17.6% is comparable with other studies assessing targeted programmes for LTB in similar settings, [17][18][19][20][21][22] and higher than a recent longitudinal study of Swiss migrant students, 23 suggesting an appropriately selected target population. The treatment completion rate of 84.3% is greater than 18,21 or comparable with 17,19 rates reported in other studies of school-age students.…”

Section: Discussionsupporting

confidence: 78%

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Tuberculosis, focussed tools and the right schools: estimated impact and cost of a targeted student screening programme for tuberculosis infection

Sawka

Geake

Stapledon

et al. 2022

Internal Medicine Journal

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Background The World Health Organization (WHO) recommends targeted screening for latent tuberculosis infection (LTBI) among high‐risk populations. Recent studies that evaluate targeted school‐based programmes in low burden settings are scarce. Aims To evaluate a school screening programme for recently arrived migrant students from moderate and high tuberculosis (TB) burden countries and estimate (1) the number of cases of active TB that were prevented and (2) the cost per case of active TB prevented. Methods Students were screened with tuberculin skin tests (TST) at schools with a high migrant population intake. Those with positive results were referred for specialist evaluation. Outcomes were retrospectively assessed using 5 years of prospectively collected data. Cost data were collected. Main outcomes measured were the number of children were diagnosed with LTBI who completed treatment, and programme costs. Results Of 4728 student screened, 295 (6.2%) were diagnosed with LTBI. Of these, 273 (92.5%) were offered preventive therapy, 242 (82.0%) commenced and 204 (69.2%) completed therapy. The number needed to screen (NNS) was 23 per completed course of preventive treatment for LTBI. Assuming a 10% lifetime risk of reactivation, the NNS was 386 per case of TB disease notification avoided. The cost of screening was A$23 932 per case of TB disease avoided. Conclusions This TB strategy is supported by the high rate of TB infection in the student group, the treatment uptake and completion rates. Cost–benefit is linked with lifetime risk of TB reactivation. Targeted school screening programmes represent an important opportunity for TB control in low‐burden settings.

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Section: Discussionsupporting

confidence: 78%

Section: Discussionsupporting

confidence: 78%

Tuberculosis, focussed tools and the right schools: estimated impact and cost of a targeted student screening programme for tuberculosis infection

Sawka

Geake

Stapledon

et al. 2022

Internal Medicine Journal

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Evaluation of a school-based program for diagnosis and treatment of latent tuberculosis infection in immigrant children

Minodier

Lamarre

Carle

et al. 2010

Journal of Infection and Public Health

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Tuberculosis: evidence review for newly arriving immigrants and refugees

Greenaway

Sandoe²,

Vissandjée³

et al. 2010

Canadian Medical Association Journal

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The casesOusman, a 32-year-old man; his 8-year-old daughter, Nene; and his 65-year-old mother, Mariama, from Casamance, Senegal, speak only Wolof and arrived in Canada six months ago from a refugee camp. What, if any, screening for latent tuberculosis should be done for this family?Active pulmonary tuberculosis was recently diagnosed in Harjit, a 65-year-old man who immigrated to Canada from India at age 32. Diabetes was diagnosed when he was 40 years old, and chronic renal failure developed one year ago that required dialysis because of the diabetes. Should screening for latent tuberculosis have been done for this man, and if so when?

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A Tuberculosis Screening and Chemoprophylaxis Project in Children from a High Risk Population in Edmonton, Alberta

Cited by 4 publications

References 5 publications

Tuberculosis, focussed tools and the right schools: estimated impact and cost of a targeted student screening programme for tuberculosis infection

Tuberculosis, focussed tools and the right schools: estimated impact and cost of a targeted student screening programme for tuberculosis infection

Evaluation of a school-based program for diagnosis and treatment of latent tuberculosis infection in immigrant children

Tuberculosis: evidence review for newly arriving immigrants and refugees

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