We report a fabrication method for laterally confining the two-dimensional electrons in InAs/AlSb single quantum wells into artificially patterned conducting wires. The minimum wire width is demonstrated to be ∼30 nm, among the smallest reported to date. The confining potential is approximately square and abrupt, and that makes the electron’s spatial distribution in the transverse direction the same as the physical width of the wire. The conducting electrons have close proximity to the surface charges, thus there is always a reduction in the elastic mean free path when the wire width decreases. Despite the reduction in mean free path, we find that the phase coherence length is approximately 1 μm at 2.2 K, a factor of 30 larger than the minimum feature size.