A two-sequence motif-based method for the inventory of gene families in fragmented and poorly annotated genome sequences
Anton Frisgaard Nørrevang,
Sergey Shabala,
Michael Palmgren
Abstract:Databases of genome sequences are growing exponentially, but, in some cases, assembly is incomplete and genes are poorly annotated. For evolutionary studies, it is important to identify all members of a given gene family in a genome. We developed a method for identifying most, if not all, members of a gene family from raw genomes in which assembly is of low quality, using the P-type ATPase superfamily as an example. The method is based on the translation of an entire genome in all six reading frames and the co… Show more
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