A two-stage discrete peristaltic micropump

Berg, Jordan M.; Anderson, Ryan; Anaya, M.; Lahlouh, B.; Holtz, Michael J.; Dallas, Tim

doi:10.1016/s0924-4247(02)00434-x

Cited by 65 publications

(49 citation statements)

References 14 publications

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“…Conversely, peristaltic pumps using elastomer as a diaphragm material [11,15,39] realize large f sp by integration. The nearest performance with the demonstrated pump within these peristaltic pumps is the one reported by Berg et al [39]. They used 3-mm chambers as well as this report and near f sp value was obtained.…”

Section: Performance Comparison With Other Micropumps On Chipmentioning

confidence: 99%

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A Peristaltic Pump Integrated on a 100% Glass Microchip Using Computer Controlled Piezoelectric Actuators

Tanaka¹

2014

Micromachines

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Lab-on-a-chip technology is promising for the miniaturization of chemistry, biochemistry, and/or biology researchers looking to exploit the advantages of a microspace. To manipulate fluid on a microchip, on-chip pumps are indispensable. To date, there have been several types of on-chip pumps including pneumatic, electroactive, and magnetically driven. However these pumps introduce polymers, metals, and/or silicon to the microchip, and these materials have several disadvantages, including chemical or physical instability, or an inherent optical detection limit. To overcome/avoid these issues, glass has been one of the most commonly utilized materials for the production of multi-purpose integrated chemical systems. However, glass is very rigid, and it is difficult to incorporate pumps onto glass microchips. This paper reports the use of a very flexible, ultra-thin glass sheet (minimum thickness of a few micrometers) to realize a pump installed on an entirely glass-based microchip. The pump is a peristaltic-type, composed of four serial valves sealing a cavity with two penetrate holes using ultra-thin glass sheet. By this pump, an on-chip circulating flow was demonstrated by directly observing fluid flow, visualized via polystyrene tracking particles. The flow rate was proportional to the pumping frequency, with a maximum flow rate of approximately 0.80 μL/min. This on-chip pump could likely be utilized in a wide range of applications which require the stability of a glass microchip.

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Section: Performance Comparison With Other Micropumps On Chipmentioning

confidence: 99%

“…The pump is composed of four serial diaphragm-type valves. In this experiment, four serial valves were used because they have higher pumping pressure than that of three or two serial valves [39] which is useful for certain pumping demonstration. Each valve has inlet and outlet holes near the center of a shallow circular chamber.…”

Section: Introductionmentioning

confidence: 99%

A Peristaltic Pump Integrated on a 100% Glass Microchip Using Computer Controlled Piezoelectric Actuators

Tanaka¹

2014

Micromachines

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“…They evaluated in detail the influence of impact of geometry, materials and pump loading on peristaltic pumping performance. Further studies of peristaltic pumping analysis and design have been communicated by Natarajan and Mokhtarzadeh-Dehghan [18], Fauci [19], Jaffrin [20] (considering inertial curvature effects), Berg et al [21] (who considered a discrete, twostage peristaltic microfluidics pump). Afifi and Gad [22] derived perturbation solutions for peristaltic flow interacting with periodic blood flow for a viscous incompressible fluid flow in a porous medium.…”

Section: Introductionmentioning

confidence: 99%

Electro-magneto-hydrodynamic peristaltic pumping of couple stress biofluids through a complex wavy micro-channel

Tripathi

Jhorar

Bég

et al. 2017

Journal of Molecular Liquids

108

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Biomimetic propulsion mechanisms are increasingly being explored in engineering sciences. Peristalsis is one of the most efficient of these mechanisms and offers considerable promise in microscale fluidics. Electrokinetic peristalsis has recently also stimulated significant attention. Electrical and magnetic fields also offer an excellent mode for regulating flows. Motivated by novel applications in electro-conductive microchannel transport systems, the current article investigates analytically the electromagnetic pumping of non-Newtonian aqueous electrolytes via peristaltic waves in a two-dimensional microchannel with different peristaltic waves propagating at the upper and lower channel wall (complex wavy scenario). The Stokes couple stress model is deployed to capture micro-structural characteristics of real working fluids. The unsteady two-dimensional conservation equations for mass and momentum conservation, electro-kinetic and magnetic body forces, are formulated in two dimensional Cartesian co-ordinates. The transport equations are transformed from the wave frame to the laboratory frame and the electrical field terms rendered into electrical potential terms via the Poisson-Boltzmann equation, Debye length approximation and ionic Nernst Planck equation. The dimensionless emerging linearized electro-magnetic boundary value problem is solved using integral methods. The influence of Helmholtz-Smoluchowski velocity (characteristic electro-osmotic velocity), couple stress length parameter (measure of the polarity of the fluid), Hartmann magnetic number, and electro-osmotic parameter on axial velocity, volumetric flow rate, time-averaged flow rate and streamline distribution are visualized and interpreted at length.

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“…Though we limited the integrated pumping principles to AC MHD and AC EOF, these are by no means the only principles suited for application in circular channels. Another principle that may for example very well be used is peristaltic pumping [50].…”

Section: Proposed Chip-based System For Cyclic Otlc Applying Continuomentioning

confidence: 99%

Cyclic electrophoretic and chromatographic separation methods

2004

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A review is given of the application of cyclic analytical methods in capillary electroseparation (CE) and liquid chromatography (LC) systems. Cyclic methods have been used since the early sixties in chromatographic systems to overcome pressure limitations to resolution. From the early nineties on they have also been applied in capillary electroseparation systems to overcome voltage limitations. Some basic theory is given, outlining the temporal development of resolution in cyclic CE and LC systems and calculating the maximal resolution that can be obtained as a function of the operational parameters of pressure and electrical field. Simple equations are given for the temporal change in the peak capacity and the loss of peaks from the systems as it occurs in some cyclic systems. Finally, a circular open tubular chromatographic system is proposed using integrated pumping and continuous detection. The performance of such a system is discussed using magnetohydrodynamic and alternating current electroosmotic pumping as examples of integrated pumps and Shah Convolution Fourier transform detection as an example of a continuous detection method.

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A two-stage discrete peristaltic micropump

Cited by 65 publications

References 14 publications

A Peristaltic Pump Integrated on a 100% Glass Microchip Using Computer Controlled Piezoelectric Actuators

A Peristaltic Pump Integrated on a 100% Glass Microchip Using Computer Controlled Piezoelectric Actuators

Electro-magneto-hydrodynamic peristaltic pumping of couple stress biofluids through a complex wavy micro-channel

Cyclic electrophoretic and chromatographic separation methods

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