1995
DOI: 10.1016/0968-0896(95)00082-r
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A urinary metabolite of Δ1-tetrahydrocannabinol. The first synthesis of 4″,5″-bisnor-Δ1-tetrahydrocannabinol-7,3″-dioic acid, and a deuterium labelled analogue

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Cited by 2 publications
(1 citation statement)
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“…The precursor cinnamic acid derivatives are synthesized by the Wittig reaction of the benzyl ether protected or unprotected hydroxy benzaldehydes or by the Knoevenagel condensation of the same derivatives with malonic acid followed by esterification . Alternatively, the 4-hydroxy-substituted 3-phenylpropionates can be synthesized from their protected 4-hydroxy-substituted benzyl chloride by the malonic ester synthesis for the synthesis of the required building blocks.…”
Section: Resultsmentioning
confidence: 99%
“…The precursor cinnamic acid derivatives are synthesized by the Wittig reaction of the benzyl ether protected or unprotected hydroxy benzaldehydes or by the Knoevenagel condensation of the same derivatives with malonic acid followed by esterification . Alternatively, the 4-hydroxy-substituted 3-phenylpropionates can be synthesized from their protected 4-hydroxy-substituted benzyl chloride by the malonic ester synthesis for the synthesis of the required building blocks.…”
Section: Resultsmentioning
confidence: 99%