A useful tool to assess quality of LIFE in rheumatoid arthritis patients that does not require a license: QOL-RA II

Isnardi, C. A.; Schneeberger, Emilce Edith; Capelusnik, Dafne; Correa, María de los Ángeles; Lim, Romina; Hu, María; Tapia, María Janina; Kerzberg, Eduardo; Blanco, Eliana; Benavídez, Federico Luján; Lucero, Luciana Gonzales; Barbaglia, A. L.; Bazzarelli, Marcela; Ficco, Hernán Maldonado; Pérez, Silvana; Hartvig, Claudia; Salcedo, Mariana; Citera, Gustavo

doi:10.1007/s10067-020-05139-8

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Disease activity of 28 joints was calculated and a score of >2.6 indicated active disease. The researchers interviewed each patient and completed the Quality of Life-Rheumatoid Arthritis II (QoL-RA II)[ 21 ] and the World Health Organization-Quality of Life (WHOQOL-BREF)[ 22 ] questionnaires using the native Kurdish language to explain each item of the questionnaire. The QoL-RA II scale consists of eight questions, and for each positive answer, a score of +1 is reported.…”

Section: Methodsmentioning

confidence: 99%

Plateletcrit is a Useful Marker in the Quality of Life Assessment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study from Erbil, Iraq

Al-Nimer

Aref

Jalal

et al. 2023

Saudi Journal of Medicine &Amp; Medical Sciences

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Background: In patients with rheumatoid arthritis (RA), hematological indices and ratios have been reported to be related to the severity of illness, and thus could potentially be useful determinants of quality of life (QoL). Objective: To evaluate the association between hematological indices or ratios, which serve as biomarkers of disease activity, and the QoL of RA patients. Materials and Methods: This study was carried out in the Rizgary Teaching Hospital in the Kurdistan region of Iraq between December 01, 2021, and March 31, 2022. All female patients with a confirmed diagnosis of RA and aged ≥18 years were included. Data relating to the disease activity score (DAS-28), biochemical measurements of the profile, and hematological indices and ratios were assessed. The QoL of each patient was assessed using the Quality of Life-Rheumatoid Arthritis II (QoL-RA II) and the World Health Organization-Quality of Life (WHOQOL-BREF) scales. Results: A total of 81 participants were included, with a median disease duration of 9 years. The median values of the hematological indices were as follows: mean corpuscular volume, 80 fL; platelet count 282 × 10 3 /mm 3 ; mean platelet volume, 9.7 fL; neutrophil-to-lymphocyte ratio, 2.76; and platelet-to-lymphocyte ratio, 170.5. In six of the eight domains of the QoL-RA II scale, the median score was ≤5, indicating poor QoL. The transformed scores of WHOQOL-BREF domains were <50. Multivariate regression analysis showed significant inverse correlations between plateletcrit and the health domains. The area under the curve of the physical, psychological, and environmental domains was <0.5 at a cutoff value of plateletcrit of 0.25. Conclusions: In RA patients, hematological indices and ratios could serve as a QoL assessment tool, particularly plateletcrit, as higher plateletcrit (≥0.25) were found to negatively impact the physical health, psychological, and environmental domains.

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Section: Methodsmentioning

confidence: 99%

Plateletcrit is a Useful Marker in the Quality of Life Assessment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study from Erbil, Iraq

Al-Nimer

Aref

Jalal

et al. 2023

Saudi Journal of Medicine &Amp; Medical Sciences

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“…There is a growing focus on patients' perception of health, disease condition and its impact on their life (Cruz-Castillo, Montero, Salazar-Ponce, & Villacís-Tamayo, 2019) . Lack of physical activity, unemployment, smoking, higher disease activity, disability and depression were also significantly associated with poorer quality of life among patients with RA (Isnardi, et al, 2020) . As well, social context impacts coping strategies and psychological reactions to RA, and can also impairs treatment adherence and hence outcomes (Sturgeon , Finan, & Zautra, 2016) .…”

Section: Introductionmentioning

confidence: 94%

Health Related Quality of Life among the Patients with Rheumatoid Arthritis

Salem

Selim

Ghadeer

et al. 2021

Egyptian Journal of Health Care

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Background: Rheumatoid Arthritis (RA) is considered a public health problem with increasing global prevalence that reached 14.9 in 2017. In addition to impairment of daily life activities, individuals diagnosed with RA suffer from psychological disorders. Aim: The study aim was to assess the health related quality of life among the patients with rheumatoid arthritis. Methods: A descriptive exploratory design was utilized to conduct the current study. Data was collected from Rheumatology Clinics in King Abdulaziz Medical City in Riyadh, Saudi Arabia over three months using a convenience sample of 300 adult patients attending Rheumatology Clinics diagnosed with RA. A self-report survey was used, and it encompassed a demographic data and World Health Organization Quality of Life (WHOQOL-BRIEF) tool. Results: A total of 300 participants suffering from RA were participated in the study. Quality of life domains four domains along with overall quality of life mean scores were significantly low among the studied participants. Physical health was the lowest (19.89 out of 35 ± 7.04, p = 0.00) among the four domains, followed by psychological (21.22 out of 30 ± 5.73, p = 0.00), then environment (28.19 ± 8.72, p = 0.00) and lastly social relations (12.06 out of 15 ± 7.29, p = 0.00) which was rated as the highest among those domains. Overall quality of life mean score was perceived on low scores by participants (81.36 out of 120 ± 28.80, p = 0.00). Conclusion: Total mean scores of all quality of life domains were significantly rated as low by the studied participants with RA. Physical health was rated as the lowest among the four domains, followed by psychological, then environment and lastly social relations which was rated as the highest among those domains. Extreme of age, being divorced and low income were significantly associated with low rating of quality of life.

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Impact of inflammation on cognitive function in patients with highly inflammatory rheumatoid arthritis

Mena-Vázquez,

Ortiz-Márquez,

Ramírez-García

et al. 2024

RMD Open

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ObjectiveTo evaluate cognitive function in patients with rheumatoid arthritis (RA) and inflammatory activity.Patients and methodsWe performed a cross-sectional study of a cohort of patients with RA initiating their first biological treatment due to moderate-to-high inflammation and a healthy control group (no inflammatory diseases) matched for age, sex and educational level. All participants underwent a comprehensive neuropsychological assessment, with cognitive impairment defined as a Montreal Cognitive Assessment (MoCA) score<26. Additional assessments included various cognitive tests (STROOP, forward and backward digit spans), anxiety and depression scales (Hospital Anxiety and Depression Scale), quality of life measures (Quality of Life-Rheumatoid Arthritis) and average inflammatory activity according to the 28-joint Disease Activity Score (DAS28)-C-reactive protein (CRP) into high activity (DAS28≥3.2) and low activity (DAS28<3.2) groups, also CRP levels and interleukin 6 (IL-6) levels were measured using an ELISA.ResultsThe study population comprised 140 participants, 70 patients with RA and 70 controls. Patients more frequently experienced cognitive impairment than controls (60% vs 40%; p=0.019) and had lower mean (SD) values in the MoCA (23.6 (3.9) vs 25.1 (3.4); p=0.019. As for subtests of the MoCA, involvement was more marked in patients than in controls for the visuospatial-executive (p=0.030), memory (p=0.026) and abstraction (p=0.039) domains. Additionally, patients scored lower on executive function, as assessed by the backward digit span test (4.0 (1.7) vs 4.7 (1.9); p=0.039). Cognitive impairment is associated with age and a lower educational level in the general population, and among patients with RA with educational level, obesity and average inflammatory activity (DAS28, CRP, and IL-6).ConclusionsPatients with RA with high inflammatory activity are more susceptible to cognitive impairment, which specifically affects the domains of visuospatial, memory, abstraction and executive function.

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A useful tool to assess quality of LIFE in rheumatoid arthritis patients that does not require a license: QOL-RA II

Cited by 4 publications

References 13 publications

Plateletcrit is a Useful Marker in the Quality of Life Assessment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study from Erbil, Iraq

Plateletcrit is a Useful Marker in the Quality of Life Assessment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study from Erbil, Iraq

Health Related Quality of Life among the Patients with Rheumatoid Arthritis

Impact of inflammation on cognitive function in patients with highly inflammatory rheumatoid arthritis

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