A Variety of Appearances of Malignant Melanoma in the Head: A Review

Escott, Edward J.

doi:10.1148/radiographics.21.3.g01ma19625

Cited by 109 publications

(75 citation statements)

References 47 publications

(44 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In fact, on enhanced CT or enhanced T1WI of MRI, pulmonary MM exhibits homogenous enhancement of the mass, while other lung malignancies usually show heterogeneity on CT scan and enhanced T1WI on MRI 7, 19. In addition, in cases of brain metastasis of MM, strong homogenous enhancement is shown on enhanced T1WI, whereas other lung malignancies usually exhibit ring enhancement 7.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary malignant melanoma with distant metastasis assessed by positron emission tomography‐computed tomography

et al. 2016

View full text Add to dashboard Cite

Melanoma is a cutaneous malignant neoplasm of melanocytes. Primary malignant melanoma (MM) of the lung is very rare. Although previous reports have described the radiologic features of pulmonary MM, its rarity means that many factors are unknown. Thus, radiologic diagnosis is very difficult. Furthermore, there is little information regarding diagnostic application and/or the usefulness of [18F]‐fluorine‐2‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography‐computed tomography (FDG‐PET‐CT) for primary pulmonary MM. A 69‐year‐old patient with a productive cough lasting three weeks was admitted to our hospital. Chest CT showed a large single mass with a multi‐lobulated margin and homogeneous enhancement in the right upper lobe, which was subsequently diagnosed as a primary pulmonary MM with multiple metastases. On PET‐CT images, the pulmonary mass and multiple bone lesions showed very increased uptakes of FDG. Considering that pulmonary metastasis from a mucocutaneous melanoma is the main differential diagnosis of primary pulmonary MM, systemic assessment of the whole body is more important than for other types of lung malignancies. This report introduces PET‐CT as a useful diagnostic modality for pulmonary MM, especially in cases of distant multiple metastases.

show abstract

Section: Discussionmentioning

confidence: 99%

Pulmonary malignant melanoma with distant metastasis assessed by positron emission tomography‐computed tomography

et al. 2016

View full text Add to dashboard Cite

show abstract

“…The former is the hyperintense T 1 and hypointense T 2 MRI pattern identified by Woodruff et al The latter MRI pattern has been found predominantly in tumors with less than 10% melanin-containing cells. These amelanotic lesions demonstrate hypointense T 1 -weighted images and hyperintense T 2 -weighted images [18]. A study of 42 lesions later diagnosed as intracranial melanoma found that 24% followed the melanotic pattern and 38% followed the amelanotic pattern on MRI [19].…”

Section: Discussionmentioning

confidence: 99%

Primary Pineal Malignant Melanoma

Bookland

Anderson²,

Biser-Rohrbaugh

et al. 2007

Pediatr Neurosurg

View full text Add to dashboard Cite

Primary pineal malignant melanomas are a rare subset of primary central nervous system melanomas. This report presents the case of a 20-year-old female patient with a primary pineal region malignant melanoma who underwent endoscopic biopsy and adjuvant therapy. Her treatment consisted of stereotactic radiation to the pineal tumor, conventional whole-brain radiation and Temodar® for the disseminated disease. She required a ventriculo-peritoneal shunt for refractory ICP problems. This report details the clinical features of the case and summarizes the literature on a rare but aggressive neoplasm.

show abstract

“…Characterizing lesions on MRI has been more widely researched in the context of brain pathology than the orbit [10,11,12,13,14,15,16,17]. Routine MRI of the brain and orbit typically includes T1-weighted and T2-weighted sequences without and with intravenous contrast administration in axial, coronal, or sagittal planes to allow a full characterization of changes in signal intensity within tissues of interest.…”

Section: Introductionmentioning

confidence: 99%

T2 Fluid-Attenuated Inversion Recovery Imaging of Uveal Melanomas and Other Ocular Pathology

Damento¹,

Koeller²,

Salomão³

et al. 2016

Ocul Oncol Pathol

View full text Add to dashboard Cite

Background/Aims: This study describes patterns of intraocular lesions on T2 fluid-attenuated inversion recovery (FLAIR) imaging, exploring a prospective role of FLAIR imaging sequence in diagnosis and treatment. Methods: A retrospective study of orbital magnetic resonance imaging (MRI) studies from the years 2000 to 2015 was performed. MRI sequences included: pre-contrast T1-weighted, T2-weighted, T2 FLAIR, and postcontrast T1 and T2 imaging gadolinium, which were evaluated by a neuroradiologist. Two cases of melanoma were correlated to their pathology. Results: Twenty-four patients with intraocular pathology were evaluated. All lesions, regardless of pigmentation, revealed previously described melanotic patterns on T1- and T2-weighted images; 80% of 10 melanomas localized were hyperintense on T2 FLAIR, which better delineated lesion margins. All of the four inflammatory pathologies on T2 FLAIR were hyperintense, as were 80% of the amelanotic neoplasms. Pathology of two large uveal melanomas paralleled the findings seen on T2 FLAIR. Conclusions: T2 FLAIR appears beneficial in the demarcation of pigmented ocular lesions and may aid in determining protein content or previous treatment. Data also promote previous assertions that blood flow impacts intensity of lesions on T2 FLAIR. Further research is warranted.

show abstract

A Variety of Appearances of Malignant Melanoma in the Head: A Review

Cited by 109 publications

References 47 publications

Pulmonary malignant melanoma with distant metastasis assessed by positron emission tomography‐computed tomography

Pulmonary malignant melanoma with distant metastasis assessed by positron emission tomography‐computed tomography

Primary Pineal Malignant Melanoma

T2 Fluid-Attenuated Inversion Recovery Imaging of Uveal Melanomas and Other Ocular Pathology

Contact Info

Product

Resources

About