A Versatile and Highly Selective Colorimetric Sensor for the Detection of Amines

Abstract

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Synthesis and Applications of Stenhouse Salts and Derivatives

“…Colorimetric sensing is a powerful technique for detection and quantification of both inorganic and organic molecules . DASA have been successfully used for the colorimetric detection of amines in solution, solid and gas phases . Secondary amines reacted with the activated furan faster than primary amines .…”

“… Colorimetric detection of amines in solution using a 20 m m MAF solution in THF. Tryptamine derivatives differentiated by the different colored stains using thin layer chromatography and staining with MAF solution …”

“…The exposure of nylon filters previously dipped in a MAF solution to dimethylamine and ammonia vapors caused a color change. Interestingly, this method was successfully used to detect food spoilage by detection of volatile amines from fish samples of cod and tilapia …”

Dual‐Mode Optical Sensing of Histamine at Nanomolar Concentrations in Complex Biological Fluids and Living Cells

“…Conventional methods for the determination of histamine (e.g., chromatography, capillary electrophoresis, fluorimetry, and immunoassays) mostly involve complex, multistep sample preparation procedures and expensive instruments, which limits their application in the real life sample analysis . On the other hand, small‐molecule‐based optical probes for biogenic amines typically suffer from problems such as poor selectivity and weak response in aqueous media . Although the specificity towards histamine could be improved by engaging transition‐metal complexes as the interactive systems [M 2+ =Zn 2+ or Ni 2+ etc.…”

“…[12][13][14][15] On the other hand, small-molecule-based optical probes for biogenic amines typically suffer from problems such as poor selectivity and weak response in aqueous media. [16][17][18][19][20][21][22][23][24] Although the specificity towards histamine could be improved by engaging transition-metal complexes as the interactive systems [M 2 + = Zn 2 + or Ni 2 + etc. ],t hese sensors are generally unsuitable for biological applicationsb ecause of their high cytotoxicity (Figure 1a).…”