A versatile Y shaped DNA nanostructure for simple, rapid and one-step detection of mycotoxins

Ochratoxin A in Dry-Cured Ham: OTA-Producing Fungi, Prevalence, Detection Methods, and Biocontrol Strategies—A Review

“…The amount of OTA can be quantitatively detected by recovering the fluorescent intensity. This method has been utilized to detect OTA in food samples with satisfactory results, thus exhibiting a promising future in food safety screening and quality monitoring [ 57 ]. Altunbas et al [ 58 ] presented the first example of a Tb3+-functionalized nanoparticle sensor for rapid, sensitive, and selective fluorescent detection of OTA.…”

Recent advances in nucleic acid signal amplification-based aptasensors for sensing mycotoxins

“…10C). 144 In this assay, Y-shaped duplex DNA arms are formed with two DNA tweezers at the two ends, resulting in the closing of the DNA tweezers and the quenching of the fluorescence. The tails at the third end contain aptamers of AFB1 and OTA, respectively, which can bind to the corresponding mycotoxins and induce the release of two DNA fragments.…”

“…(B) The construction of a dual DNA tweezer-based aptasensor for the simultaneous detection of AFB1 and OTA 143. (C) The construction of a versatile Y-shaped DNA nanostructure-based aptasensor for the detection of AFB1 and OTA 144. (D) The construction of a twocolor aptasensor based on HCR and DNA tweezers for the OTA assay 145.…”

Dual-amplification colorimetric detection of bisphenol A based on catalytic hairpin assembly and DNAzyme-caused fragment self-assembly hybridization chain reaction

“…There are many studies that combine these two enzyme-free signal amplication techniques for uorescent, colorimetric and electrochemical biosensors to greatly improve their sensitivity. [15][16][17][18][19][20] Traditional HCR uses two hairpins to open and hybridize with each other in an alternating manner, but the efficiency is limited by its locked structure. 21 Therefore, it is necessary to develop a more efficient amplication technology for BPA detection.…”