A Very Rare Cause of Bicytopenia; The Use of Vitex Acnu Castus

Abstract

Vitex Agnu Castus dry extract BNO 1095 is used in many indications, mainly premenstrual syndrome. Nausea, headache, acne, etc. are the main side effects. The use of BNO 1095 was learned from the history of a 27-year-old female patient who was examined for bicytopenia etiology. Serological tests results were within normal limits and the bone marrow biopsy clonality result suggested that this might be related to non-neoplastic autoimmune processes. The response to methylprednisolone treatment was accepted as a finding supporting this result. Although there are many reasons in the etiology of bicytopenia, the use of herbal medicine should always be considered. This is the first case in the literature demostrating that this herbal medicine causes bicytopenia.