In this paper we report the first identification of jellyfish galaxies in the Perseus cluster (Abell 426). We identified four jellyfish galaxies (LEDA 2191078, MCG +07-07-070, UGC 2654, UGC 2665) within the central 2 • × 2 • (2.6 Mpc × 2.6 Mpc) of Perseus based on the presence of one-sided radio continuum tails that were detected at 144 MHz by the LOw Frequency ARray (LOFAR). The observed radio tails, as well as the orientation of morphological features in the rest-frame optical, are consistent with these four galaxies being impacted by ram pressure stripping as they orbit through the Perseus intracluster medium. By combining the LOFAR imaging at 144 MHz with 344 MHz imaging from the Karl G. Jansky Very Large Array, we derived spectral indices for the disks and the stripped tails of these jellyfish galaxies. We show that the spectral indices over the galaxy disks are quite flat, while the indices of the stripped tails are substantially steeper. We also identified a number of compact Hα + [Nii] sources with narrowband imaging from the Isaac Newton Telescope. These sources are brighter along the leading side of the galaxy (i.e., opposite to the direction of the stripped tail), which is consistent with ram pressure induced star formation. Lastly, consistent with previous works in other clusters, we find that these jellyfish galaxies show enhanced radio luminosities for their observed star formation rates. Given the small distance to the Perseus cluster (D ∼ 70 Mpc, 1 340 pc), these galaxies are excellent candidates for multiwavelength follow-up observations to probe the impact of ram pressure stripping on galaxy star formation at subkiloparsec scales.