A visible light induced photoelectrochemical aptsensor constructed by aligned ZnO@CdTe core shell nanocable arrays/carboxylated g-C3N4 for the detection of Proprotein convertase subtilisin/kexin type 6 gene

Pang, Xuehui; Pan, Jihong; Gao, Picheng; Wang, Youying; Wang, Liguo; Du, Bin; Wei, Qin

doi:10.1016/j.bios.2015.06.030

Cited by 52 publications

(17 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5 C). PCSK6 was the most significantly elevated gene in the liver of AKAP12 Δhep mice and is strongly associated with inflammation and autoimmune disease [ 26 , 27 ] ( Fig. 5 C).…”

Section: Resultsmentioning

confidence: 99%

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

Wang

et al. 2022

Redox Biology

View full text Add to dashboard Cite

“…5 C). PCSK6 was the most significantly elevated gene in the liver of AKAP12 Δhep mice and is strongly associated with inflammation and autoimmune disease [ 26 , 27 ] ( Fig. 5 C).…”

Section: Resultsmentioning

confidence: 99%

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

Wang

et al. 2022

Redox Biology

View full text Add to dashboard Cite

“…The g-C 3 N 4 QDs were obtained by ultrasound treatment of bulk g-C 3 N 4 , 15 g of which were prepared as described in the literature [82]. Melamine powder (15 g) was placed in a covered ceramic crucible and heated in a muffle furnace with a ramp rate of 2 °C/min to 550 °C and held for 4 h. After cooling naturally to room temperature, bulk g-C 3 N 4 powder was removed from the muffle furnace.…”

Section: Methodsmentioning

confidence: 99%

Construction of self-powered cytosensing device based on ZnO nanodisks@g-C3N4 quantum dots and application in the detection of CCRF-CEM cells

Pang

Cui

et al. 2018

Nano Energy

Self Cite

View full text Add to dashboard Cite

We herein report a self-powered and renewable cytosensing device based on ZnO nanodisks(NDs)@g-C3N4 quantum dots. The device features enhanced photoelectrochemical (PEC) activity compared to ZnO NDs or g-C3N4 QDs alone. The enhanced PEC ability is attributed to the synergistic effect of the high visible light sensitivity of g-C3N4 QDs and the staggered band alignment heterojunction structure with suitable band offset, which affords higher photoelectron transfer and separation efficiency. In addition, the hybridization of g-C3N4 QDs further accelerates interfacial electron transfer and blocks recombination between electron donors and photo-generated holes. The device was applied to the detection of CCRF-CEM cells. By conjugation to Sgc8c aptamer, which preferentially interacts with membrane-bound PTK7 on CCRF-CEM membranes, capture of target CCRF-CEM cells resulted in a decrease in apparent power output, which was then exploited for the ultrasensitive detection of the target cells. This decrease in power output can be recovered by simply increasing the temperature to release the cells, thus recycling the cytosensing performance. The device displayed a linear relationship between the change of power output and the logarithm of the cell concentration from 20 to 20,000 cell/mL (R2 = 0.9837) and a detection limit down to 20 cell/mL, as well as excellent selectivity and reproducibility. Thus, this ZnO NDs@g-C3N4 QDs-based device exhibits high potential for the detection of CCRF-CEM cells.

show abstract

“…The XRD pattern of the TiO 2 NNs@MoO 3 array is shown in Figure A. The diffraction peaks located at 27.6°, 36.2°, 39.2°, 41.5°, 44.2°, 54.5°, 56.9°, 69.1°, and 69.9° and marked with heart shapes correspond to rutile TiO 2 according to JCPDS card no. 21-1276.…”

Section: Resultsmentioning

confidence: 99%

Photoelectrochemical Cytosensing of RAW264.7 Macrophage Cells Based on a TiO₂ Nanoneedls@MoO₃ Array

Pang

Bian²,

et al. 2017

Anal. Chem.

Self Cite

View full text Add to dashboard Cite

We have developed a photoelectrochemical (PEC) cytosensor for ultrasensitive detection of RAW264.7 cells by the signal change of a TiO nanoneedles (NNs)@MoO array. For the first time, a TiO NNs@MoO array was adopted for the fabrication of the cytosensor for the signal output. The well-matched alignment of TiO NNs and MoO efficiently suppresses the recombination of photogenerated electron and hole (e/h) pairs for improved photon-to-current conversion efficiency. The RAW264.7 cell and F4/80 antibody could form the biocomplexes because of the specific recognition between each other. The constructed PEC cytosensor based on the TiO NNs@MoO array displayed good PEC property for detection of RAW264.7 cells. The numbers of RAW264.7 cells are directly detected through the decrement of photocurrent intensity, due to the increased steric hindrance when RAW264.7 cells are captured. The PEC cytosensor showed an ultrasensitive response to RAW264.7 cells with a linear range of 50-15 000 cells/mL and a detection limit of 50 cells/mL. The designed cytosensor based on a TiO NNs@MoO array offers an ideal platform to detect RAW264.7 cells with excellent stability, reproducibility, and selectivity and served as a model for the fabrication of cytosensors for other cells.

show abstract

A visible light induced photoelectrochemical aptsensor constructed by aligned ZnO@CdTe core shell nanocable arrays/carboxylated g-C3N4 for the detection of Proprotein convertase subtilisin/kexin type 6 gene

Cited by 52 publications

References 73 publications

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

Construction of self-powered cytosensing device based on ZnO nanodisks@g-C3N4 quantum dots and application in the detection of CCRF-CEM cells

Photoelectrochemical Cytosensing of RAW264.7 Macrophage Cells Based on a TiO₂ Nanoneedls@MoO₃ Array

Contact Info

Product

Resources

About

A visible light induced photoelectrochemical aptsensor constructed by aligned ZnO@CdTe core shell nanocable arrays/carboxylated g-C3N4 for the detection of Proprotein convertase subtilisin/kexin type 6 gene

Cited by 52 publications

References 73 publications

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

Construction of self-powered cytosensing device based on ZnO nanodisks@g-C3N4 quantum dots and application in the detection of CCRF-CEM cells

Photoelectrochemical Cytosensing of RAW264.7 Macrophage Cells Based on a TiO2 Nanoneedls@MoO3 Array

Contact Info

Product

Resources

About

Photoelectrochemical Cytosensing of RAW264.7 Macrophage Cells Based on a TiO₂ Nanoneedls@MoO₃ Array