In this paper, we present a novel thermoresistive gas flow sensor with a high-yield and low-cost volume production by using front-side microfabricated technology. To best improve the thermal resistance, a micro-air-trench between the heater and the thermistors was opened to minimize the heat loss from the heater to the silicon substrate. Two types of gas flow sensors were designed with the optimal thermal-insulation configuration and fabricated by a single-wafer-based single-side process in (111) wafers, where the type A sensor has two thermistors while the type B sensor has four. Chip dimensions of both sensors are as small as 0.7 mm × 0.7 mm and the sensors achieve a short response time of 1.5 ms. Furthermore, without using any amplification, the normalized sensitivity of type A and type B sensors is 1.9 mV/(SLM)/mW and 3.9 mV/(SLM)/mW for nitrogen gas flow and the minimum detectable flow rate is estimated at about 0.53 and 0.26 standard cubic centimeter per minute (sccm), respectively.Micromachines 2020, 11, 205 2 of 10 insulation membrane is formed by potassium hydroxide (KOH) anisotropic etching from the wafer backside. The anisotropic etching-induced inclined sidewalls cause the chip size to be quite large and the back-sided KOH etching is time-consuming, which yield a higher batch-fabrication cost [10]. Thus, developing a new strategy to minimize the chip size for realizing batch-fabrication with a lower cost is an important issue. Recently, a commercial 0.35 µm 2P4M microelectromechanical systems (MEMS) process was used in [11] to fabricate a sensor from the front-side of a (100) wafer. The approach decreased the chip-size and fabrication cost. However, the insulation membrane was released through XeF 2 isotropic etching, Thus, a depth-limited insulation cavity was formed, which would increase the heat loss, lower the thermal resistance and cause a relatively lower sensitivity of the sensor. Here, this paper expands on preliminary research presented in [12] and explores a tiny-sized ultrasensitive thermoresistive gas flow sensor that is single-side processed in an ordinary single-polished (111) silicon wafer. By changing the number of thermoresistive sensors, we developed two types of differential thermoresistive gas flow sensors, a half-bridge type and a full-bridge type.