A Ward Test for Sugar in Fæces

Kerry, Knowles; Anderson, Charlotte M.

doi:10.1016/s0140-6736(64)91777-5

Cited by 132 publications

(67 citation statements)

References 6 publications

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“…The following criteria helped to establish the diagnosis of paragonimiasis: (1) prompt the clinician to investigate the stool for the presence of sugars by chromatography (Soeparto et al, 1972;Ament, 1973 Stools were collected from plastic-backed disposable nappies and deep frozen within 2 hours of collection. The concentration of reducing substances was estimated with Clinitest (Ames) tablets using the method described by Kerry and Anderson (1964). The pH was estimated with pH papers (Whatman-BDH, narrow range).…”

Section: Discussionmentioning

confidence: 99%

Faecal excretion of oligosaccharides and other carbohydrates in normal neonates.

Whyte¹,

Homer²,

Pennock³

1978

Arch Dis Child

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Chromatographic analysis of sugars in the stools of 40 normal newborn infants has shown the presence of an oligosaccharide in 85% of samples. The oligosaccharide has been shown to contain fucose (6-deoxygalactose), glucose, and galactose and is present in normal breast milk. In addition fucose has also been found in the presence of galactose in some samples and is probably a breakdown product of milk oligosaccharides. These findings, which affect the interpretation of faecal sugar excretion, have not been described previously.

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Section: Discussionmentioning

confidence: 99%

Faecal excretion of oligosaccharides and other carbohydrates in normal neonates.

Whyte¹,

Homer²,

Pennock³

1978

Arch Dis Child

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“…A. Walker-Smith tion of excess reducing substances in the stool from infants being fed with a lactose containing diet is the most reliable way to diagnose clinical lactose intolerance in infancy, the diarrhoea rapidly responding to the elimination of lactose (Kerry and Anderson, 1964;Soeparto et al, 1972). Similarly, the return of diarrhoea after an oral load of lactose given to a child who is having a lactose free diet is a reliable way to diagnose continuing clinical lactose intolerance (Anderson and Burke, 1975 McGill, 1966).…”

Section: Discussionmentioning

confidence: 99%

Reinvestigation of lactose intolerant children: lack of correlation between continuing lactose intolerance and small intestinal morphology, disaccharidase activity, and lactose tolerance tests.

Harrison¹,

Walker-Smith²

1977

Gut

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SUMMARY Thirty children on a lactose-free diet aged from 2-38 months who had previously been diagnosed as having secondary lactose intolerance were reinvestigated on 32 occasions by an oral lactose tolerance test, small intestinal biopsy, and measurement of disaccharidase activity in order to detect the presence of continuing lactose intolerance before reintroduction of milk. No correlation was found between continuing lactose intolerance, as diagnosed by the development of watery stools containing excess reducing substances after an oral load of lactose, and maximum blood glucose rise during a lactose tolerance test, lactase levels, and small intestinal morphology.

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“…Stool chromatography in 13 showed lactose, glucose, galactose, or a variable combination of these sugars-that is, a pattern consistent with lactose malabsorption. The stools of 3 infants contained oligosaccharides or maltose only.Chromatography of urine from 60 normal neonates showed detectable sugars in 11 but only 3 had levels above 50 mg/100 ml.Reports on the sugar content of the stools and urine of normal neonates are conflicting, though in older children more than 0 5% of reducing substances in the stools or more than 15 mg/100 ml in the urine are generally agreed to be abnormal (Kerry and Anderson, 1964;Menzies and Seakins, 1969). Davidson and Mullinger (1970) Bickel (1961), studying 155 specimens of urine from 88 normal neonates, found the mean 'normal' lactose to be between 20 mg/100 ml and 50 mg/100 ml between the third and seventh day of life.…”

mentioning

confidence: 99%

“…There was no absolute certainty that stools were not contaminaed by urine, although every endeavour was made to avoid this. The converse could easily be seen on inspection of the urine container at the time of testing and any faecally contaminated specimen was discarded.After thawing, stool and urine specimens were first tested for reducing substances with Clinitest tablets (Kerry and Anderson, 1964 …”

mentioning

confidence: 99%

Stool and urinary sugars in normal neonates.

Counahan¹,

Walker-Smith²

1976

Archives of Disease in Childhood

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. Stool and urinary sugars in normal neonates. The pH of the stool and the amount of reducing substances present were observed in 51 normal neonates aged 5 to 8 days. A stool pH of 5 or less was found in 6, 4 of whom were exclusively breast fed. Reducing substances, 0 5 % or more, were found in the stools of 16. Stool chromatography in 13 showed lactose, glucose, galactose, or a variable combination of these sugars-that is, a pattern consistent with lactose malabsorption. The stools of 3 infants contained oligosaccharides or maltose only.Chromatography of urine from 60 normal neonates showed detectable sugars in 11 but only 3 had levels above 50 mg/100 ml.Reports on the sugar content of the stools and urine of normal neonates are conflicting, though in older children more than 0 5% of reducing substances in the stools or more than 15 mg/100 ml in the urine are generally agreed to be abnormal (Kerry and Anderson, 1964;Menzies and Seakins, 1969). Davidson and Mullinger (1970) Bickel (1961), studying 155 specimens of urine from 88 normal neonates, found the mean 'normal' lactose to be between 20 mg/100 ml and 50 mg/100 ml between the third and seventh day of life. Haworth and McCredie (1956) found that about half of 50 normal breast-fed babies had reducing sugars in their urine at some time during the first weeks of life and a substantial minority had more than 50 mg/100 ml, yet more than 15 mg/100 ml of sugar in the urine of neonates who have had surgery has been regarded by some workers as confirming a diagnosis of sugar intolerance (Howat and Aaronson, 1971 urine sugar levels in normal breast-and bottle-fed newborn infants. This paper reports the results.Patients and methods Specimens of stool or urine, or both, were obtained from 73 infants in the lying-in wards of the Mother's Salvation Army Hospital, Clapton. At the time of collection 53 of the infants were 5 days old, 17 were 6 days old, 2 were 4 days old, and 1 was 8 days old. Stools alone were collected from 13 infants, urine alone from 22 and both stools and urine from 38. Their birth weight ranged from 2 -3 to 4 -2 kg (mean 3 * 19 kg) and their gestation from 35 weeks to 42 weeks (mean 38 -1 weeks).Feeds were classified as breast, bottle (in all cases prepacked half cream Cow and Gate), and mixedthat is, breast-fed plus complements of half cream Cow and Gate. This formula contains 7-1 g lactose/100 ml but no sucrose.Urine was collected at random times into U-bags (Hollister) and then deep-frozen in plastic bottles.Stools were collected on the same day into a nappy lined with plastic and were stored in plastic containers in a deep-freeze within 2 hours, in most cases. There was no absolute certainty that stools were not contaminaed by urine, although every endeavour was made to avoid this. The converse could easily be seen on inspection of the urine container at the time of testing and any faecally contaminated specimen was discarded.After thawing, stool and urine specimens were first tested for reducing substances with Clinitest tablets (Kerry and Anders...

show abstract

A Ward Test for Sugar in Fæces

Cited by 132 publications

References 6 publications

Faecal excretion of oligosaccharides and other carbohydrates in normal neonates.

Faecal excretion of oligosaccharides and other carbohydrates in normal neonates.

Reinvestigation of lactose intolerant children: lack of correlation between continuing lactose intolerance and small intestinal morphology, disaccharidase activity, and lactose tolerance tests.

Stool and urinary sugars in normal neonates.

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