A water‐soluble, AIE‐active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro‐2A cells

Abstract

A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water-soluble and exhibits aggregation-induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells, providing useful information of cellular morphology and intracellular aggregation or motion.

Polymerization-Enhanced Two-Photon Photosensitization for Precise Photodynamic Therapy

“…The synthetic routes of monomers, M1, M2, and M3, are presented in Scheme S1, which have been reported in the literature. Tetrahydrofuran (THF) was distilled under dry nitrogen prior to use from sodium benzophenone ketyl.…”

Nonlinear nanophotonic devices in the ultraviolet to visible wavelength range

“…In previous work, it has demonstrated large NLO coefficients, particularly the first hyperpolarizability or the second-order NLO coefficient, and the four-leaf clover architecture facilitates the design of push-pull chromophores that allows electron charge transfer across the π conjugation of the TPE molecule [170][171][172][173][174][175][176][177][178][179]. It has previously been used successfully as an imaging agent [155,155,180], and, in contrast to many fluorophores, it is well-known for exhibiting aggregation-induced-emission (AIE) [171,181] in which the emission intensity increases as the molecules aggregate. One study measured the nonlinear optical activity of a series of TPE structures ( Figure 6) [170].…”