superhydrophobic materials have been reported. [12] However, most of these materials make use of petroleum derivatives and fluorinated compounds, [13] as well as textured inorganic materials, [14] which serve as substrates for surface chemical functionalization. These materials are not inherently biodegradable and thus pose a challenge in terms of environmental impact and recyclability. Especially longchain fluorinated compounds, which are used often to obtain liquid repellency, are difficult to degrade and tend to bioaccumulate. [15,16] Furthermore, even if these substances degrade after a prolonged period, some of their by-products are known to be toxic, such as perfluorooctanoic acid [17] and perfluorooctanesulfonate. [18] Recent studies have reported the use of more sustainable methods and materials to obtain the self-cleaning effect. These include the use of biodegradable polymers and natural materials, [19] waterborne spray approaches, [20] alcoholic solvent environment, [21] silicone-based biocompatible materials, [22] reactive polymeric materials, [23] fluorine-free substances, [24][25][26] cellulose-based, [27] and natural wax-based material compositions. [28,29] The use of the latter two materials (cellulose and wax) is inspired from the fact that they are the main constituents of a broad selection of plants, including the well-known Lotus leaf. [30] Cellulose is the material that mainly constitutes the substrate and is responsible for the leaf's mechanical properties and microroughness (the latter in the form of macropapillae) in a wide range of plants. On the other hand, the wax nanocrystals cover the microtopography and are responsible for the superhydrophobicity, bothThe development of fully organic (cellulose/wax based), biodegradable, and hierarchically textured superhydrophobic material, inspired by natural, selfcleaning plants, like the Lotus leaf is reported. The developed material can reproduce in a controllable and artificial manner the chemical composition and material properties of these natural surfaces. At the same time, the fabrication protocol described here enables realization of properties beyond the ones found in the natural leaves, by allowing facile tuning of the topographical and mechanical properties. The surface topography consists of a micropillar structure assembly with, to the best of the authors' knowledge, the highest to date reported aspect ratio (7.6) for cellulose materials. Additionally, control and tunability of the material's mechanical properties are also demonstrated, which is rendered softer (down to 227 MPa Young's modulus from 997 MPa base value) by adding glycerol as a natural plasticizer. Finally, the self-cleaning properties are demonstrated and the biodegradability of the material is evaluated in a period of ≈3 months, which confirms full biodegradation. Additionally, water drop and jet impact, and folding tests demonstrate that the material can reasonably sustain its wettability properties. Such a truly bioinspired and biodegradable material system could fin...