A wearable cardioverter defibrillator with a low false alarm rate

Poole, Jeanne E.; Gleva, Marye J.; Birgersdotter‐Green, Ulrika; Branch, Kelley R.; Doshi, Rahul N.; Salam, Tariq; Crawford, Thomas; Willcox, Mark E.; Sridhar, Arun; Mikdadi, Ghiath; Beinart, Sean C.; Cha, Yong‐Mei; Russo, Andrea M.; Rowbotham, Ron; Sullivan, Joseph; Gustavson, Laura; Kivilaid, Kaisa

doi:10.1111/jce.15417

Cited by 9 publications

(4 citation statements)

References 23 publications

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“…This difference in daily wear hours may have several reasons, among others a fast recovery of symptoms in younger patients, wearing discomfort, inadequate education, lack of high‐risk warning, undiligent follow‐up and being physically more active. Moreover, false alarms due to wear discomfort and electrocardiogram noise might also be reasons 10 . The ‘symptom’ in heart failure might not only be depicted by NYHA class but also should be multifactorial (subjective feeling, blood biomarkers like BNP, Creatinin and objective clinical parameters like EF, 6‐MWT, Spirometry).…”

Section: Discussionmentioning

confidence: 99%

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Age differences of patients treated with wearable cardioverter defibrillator: Data from a multicentre registry

El‐Battrawy

Tenbrink

Kovacs³

et al. 2023

Eur J Clin Investigation

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Background Wearable cardioverter defibrillators (WCD) are used as a ‘bridging’ technology in patients, who are temporarily at high risk for sudden cardiac death (SCD). Several factors should be taken into consideration, for example patient selection, compliance and optimal drug treatment, when WCD is prescribed. We aimed to present real‐world data from seven centres from Germany and Switzerland according to age differences regarding the outcome, prognosis, WCD data and compliance. Materials and Methods Between 04/2012 and 03/2021, 1105 patients were included in this registry. Outcome data according to age differences (old ≥45 years compared to young <45 years) were analysed. At young age, WCDs were more often prescribed due to congenital heart disease and myocarditis. On the other hand, ischaemic cardiomyopathy (ICM) was more present in older patients. Wear days of WCD were similar between both groups (p = .115). In addition, during the WCD use, documented arrhythmic life‐threatening events were comparable [sustained ventricular tachycardia: 5.8% vs. 7.7%, ventricular fibrillation (VF) .5% vs. .6%] and consequently the rate of appropriate shocks was similar between both groups. Left ventricular ejection fraction improvement was documented over follow‐up with a better improvement in younger patients as compared to older patients (77% vs. 63%, p = .002). In addition, at baseline, the rate of atrial fibrillation was significantly higher in the older age group (23% vs. 8%; p = .001). The rate of permanent cardiac implantable electronic device implantation (CiED) was lower in the younger group (25% vs. 36%, p = .05). The compliance rate defined as wearing WCD at least 20 h per day was significantly lower in young patients compared to old patients (68.9% vs. 80.9%, p < .001). During the follow‐up, no significant difference regarding all‐cause mortality or arrhythmic death was documented in both groups. A low compliance rate of wearing WCD is predicted by young patients and patients suffering from non‐ischaemic cardiomyopathies. Conclusion Although the compliance rate in different age groups is high, the average wear hours tended to be lower in young patients compared to older patients. The clinical events were similar in younger patients compared to older patients.

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Section: Discussionmentioning

confidence: 99%

“…Moreover, false alarms due to wear discomfort and electrocardiogram noise might also be reasons. 10 The 'symptom' in heart failure might not only be depicted by NYHA class but also should be multifactorial (subjective feeling, blood biomarkers like BNP, Creatinin and objective clinical parameters like EF, 6-MWT, Spirometry).…”

Section: Predictors Of Compliancementioning

confidence: 99%

Age differences of patients treated with wearable cardioverter defibrillator: Data from a multicentre registry

El‐Battrawy

Tenbrink

Kovacs³

et al. 2023

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

“…1 The reasons for patient reluctance to continue with this device revolves around two issues: wear discomfort and frequent false alarms that are not only a nuisance but may interrupt sleep and generate anxiety. The study by Poole et al 2 The function of the proprietary algorithm is well described by the authors in their report. The study enrolled implantable cardioverter-defibrillator (ICD) patients, thereby permitting comparison of WCD diagnostics with retrieved intracardiac electrograms in each individual.…”

mentioning

confidence: 93%

“… 1 The reasons for patient reluctance to continue with this device revolves around two issues: wear discomfort and frequent false alarms that are not only a nuisance but may interrupt sleep and generate anxiety. The study by Poole et al 2 in this issue reports the function of a novel WCD platform that aimed to resolve these persistent problems. The results are impressive.…”

mentioning

confidence: 99%