2023
DOI: 10.2196/47590
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A Web-Based Calculator to Predict Early Death Among Patients With Bone Metastasis Using Machine Learning Techniques: Development and Validation Study

Mingxing Lei,
Bing Wu,
Zhicheng Zhang
et al.

Abstract: Background Patients with bone metastasis often experience a significantly limited survival time, and a life expectancy of <3 months is generally regarded as a contraindication for extensive invasive surgeries. In this context, the accurate prediction of survival becomes very important since it serves as a crucial guide in making clinical decisions. Objective This study aimed to develop a machine learning–based web calculator that can provide an accur… Show more

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Cited by 9 publications
(2 citation statements)
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“…SHAP allows for a global evaluation of the model by determining the marginal contribution of features to the model output. Complementing the SHAP method, the Local Interpretable Model-Agnostic Explanations (LIME) method improves the interpretability of the best model and its transparency in clinical practice ( 19 ). LIME calculates the risk of premature death and assigns individual weights to each variable, helping to understand changes in estimated probabilities under different observation settings and making the model more distinct.…”
Section: Methodsmentioning
confidence: 99%
“…SHAP allows for a global evaluation of the model by determining the marginal contribution of features to the model output. Complementing the SHAP method, the Local Interpretable Model-Agnostic Explanations (LIME) method improves the interpretability of the best model and its transparency in clinical practice ( 19 ). LIME calculates the risk of premature death and assigns individual weights to each variable, helping to understand changes in estimated probabilities under different observation settings and making the model more distinct.…”
Section: Methodsmentioning
confidence: 99%
“…SHAP allows for a global evaluation of the model by determining the marginal contribution of features to the model output. Complementing the SHAP method, the Local Interpretable Model-Agnostic Explanations (LIME) method improves the interpretability of the best model and its transparency in clinical practice (19). LIME calculates the risk of premature death and assigns individual weights to each variable, helping to understand changes in estimated probabilities under different observation settings and making the model more distinct.…”
Section: Model Interpretability and Variable Importancementioning
confidence: 99%