2014
DOI: 10.1093/database/bau101
|View full text |Cite
|
Sign up to set email alerts
|

A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools

Abstract: The publicly available online database MelGene provides a comprehensive, regularly updated, collection of data from genetic association studies in cutaneous melanoma (CM), including random-effects meta-analysis results of all eligible polymorphisms. The updated database version includes data from 192 publications with information on 1114 significantly associated polymorphisms across 280 genes, along with new front-end and back-end capabilities. Various types of relationships between data are calculated and vis… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
8
0

Year Published

2015
2015
2021
2021

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 9 publications
(8 citation statements)
references
References 19 publications
0
8
0
Order By: Relevance
“…The MelGene database represents a comprehensive, systematically updated, online synopsis of genetic association studies in CM (Athanasiadis et al, 2014). This freely available database is curated by experienced researchers to summarize the volume of the evidence between genetic variants and CM.…”
Section: Discussionmentioning
confidence: 99%
“…The MelGene database represents a comprehensive, systematically updated, online synopsis of genetic association studies in CM (Athanasiadis et al, 2014). This freely available database is curated by experienced researchers to summarize the volume of the evidence between genetic variants and CM.…”
Section: Discussionmentioning
confidence: 99%
“…Other mutations have been identified in genes of more moderate penetrance, including BAP1, TERT, POT1, ACD, TERF2IP and MITF [9] . Genome-wide association studies have also revealed numerous recurring single nucleotide polymorphisms (SNPs) associated with melanoma risk [10][11][12][13] .…”
Section: Germ-line Susceptibilitymentioning
confidence: 99%
“…Most of these SNPs (n ¼ 52) were selected from MelGene (www.melgene.org), a continuously updated database for CM genetic association studies (Antonopoulou et al, 2015;Athanasiadis et al, 2014;Chatzinasiou et al, 2011). We further included seven GWAS SNPs from a recent GWAS metaanalysis, which were tested in our cohort as part of the replication phase (Law et al, 2015).…”
Section: Snp Selectionmentioning
confidence: 99%