A Well‐Defined Dinuclear Telluronic Acid [RTe(μ‐O)(OH)₃]₂

Abstract

Two for Te: The ditelluronic acid 3 is the first heavy congener of sulfonic and selenonic acids and is obtained by the O2 oxidation of the tellurinate 2 in the presence of [18]crown‐6. Compound 2 is prepared by the reaction of the ditellurinic acid 1 with NaH. The direct oxidation of 1 to 3 using strong oxidants, such as H2O2, KMnO4, and NaIO4 failed.

Novel μ2-oxo-bridged dinuclear aryltelluronic triorganotin(IV) esters: syntheses, structural characterizations, and in vitro cytotoxicity

“…μ 2 -oxo-bridged dinuclear aryltelluronic acids were prepared by a standard method [13,14]. The melting points were obtained with a Kofler micro-melting point apparatus and are uncorrected.…”

“…With these in mind, we turn our attention to incorporate bioactive Te into the structures of organotin complexes to obtain organotin tellurate as a strategy of preparation of new drug candidates in which the metal and the aryltelluronic ligands could act synergistically. Herein, μ 2 -oxo-bridged dinuclear aryltelluronic acids were synthesized [13,14], followed by treatment with triorganotin chloride in a 1 : 4 ratio which successfully afforded dinuclear aryltelluronic triorganotin esters [ArTe( μ-O)(OH)(OSnR 3 ) 2 ] 2 (Ar = n-propyl-Ph, R = Me: 1, R = Ph: 2; Ar = i-propyl-Ph, R = Me: 3, R = Ph: 4). The complexes were characterized by X-ray crystallography, elemental analysis, FT-IR and NMR ( 1 H, 13 C, 119 Sn) spectroscopy, and were tested for in vitro cytotoxicity against human lung cancer cells (A549) and human hepatocellular carcinoma cells (HepG2).…”

Syntheses, Characterizations, Crystal structures, and Antitumor Activities of Arenetelluronic Triorganotin Esters

“…947.23 (16) 1008.13 (16) 1008.13 (16) 3981 (3) 1001.19 (16) 3997.3(6) the basis of this, we can conclude that tetracoordinated trialkyltin centers are contained in complexes 1, 3, and 5. The other group is mainly between -102.7 and -117.6 (complexes 2, 4, and 6).…”

“…The syntheses of μ 2 -oxo-bridged dinuclear aryltelluronic acid ligands [ArTe(μ-O)(OH) 3 ] 2 were carried out according to a previously reported method [15][16][17]. Complexes 1-6 were obtained by using arenetelluronic acids and potassium hydroxide to react with the corresponding R 3 SnCl (R =…”

“…Arenetelluronic acids were prepared by a standard method reported in the literature [15][16][17]. The melting points were obtained with a Kofler micromelting point apparatus and are uncorrected.…”