A wet-adhesive carboxymethylated yeast β-glucan sponge with radical scavenging, bacteriostasis and anti-inflammatory functions for rapid hemostasis

Zhou, Zongbao; Xiao, Jiangwei; Huang, Sheng; Wu, Huixiang; Guan, Shuwen; Wu, Tingting; Yu, Shan Ping; Huang, Shuai; Gao, Botao

doi:10.1016/j.ijbiomac.2023.123158

Cited by 17 publications

(1 citation statement)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The superior hemostatic ability may be attributed to the superior tissue adhesion of the CMYG sponge, which resulted in hemostasis through rapid wound blockage. In addition, the sponge has antioxidant, anti-infective, anti-inflammatory, and cell proliferative properties that favor further wound repair …”

Section: Polysaccharide Hemostatic Materialsmentioning

confidence: 99%

Recent Advances in Topical Hemostatic Materials

Liu,

Zhang,

Yao

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Untimely or improper treatment of traumatic bleeding may cause secondary injuries and even death. The traditional hemostatic modes can no longer meet requirements of coping with complicated bleeding emergencies. With scientific and technological advancements, a variety of topical hemostatic materials have been investigated involving inorganic, biological, polysaccharide, and carbonbased hemostatic materials. These materials have their respective merits and defects. In this work, the application and mechanism of the major hemostatic materials, especially some hemostatic nanomaterials with excellent adhesion, good biocompatibility, low toxicity, and high adsorption capacity, are summarized. In the future, it is the prospect to develop multifunctional hemostatic materials with hemostasis and antibacterial and anti-inflammatory properties for promoting wound healing.

show abstract

Section: Polysaccharide Hemostatic Materialsmentioning

confidence: 99%

Recent Advances in Topical Hemostatic Materials

Liu,

Zhang,

Yao

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

Novel Natural Polymer‐Based Hydrogel Patches with Janus Asymmetric‐Adhesion for Emergency Hemostasis and Wound Healing

Sun,

Zhou,

Lai

et al. 2024

Adv Funct Materials

View full text Add to dashboard Cite

An asymmetrical wound dressing functions akin to human skin by serving as a protective barrier between a wound and its immediate environment. However, significant challenges persist concerning the robust adhesion and asymmetrical adhesion properties of hydrogels, particularly when applied in emergency hemostasis and wound healing contexts. Herein, the study has successfully synthesized hydrogel patches with Janus asymmetric‐adhesion, denoted as HGO‐C, exclusively comprised of natural polymers. This achievement is realized through the assembly of adhesive hydrogel (HGO) and non‐adhesive hydrogel (CGC), thereby amalgamating their distinct functionalities. The non‐adhesive hydrogel component served as a physical shield and safeguarding the wound against contamination, while the adhesive hydrogel, when in contacted with the wound surface, firmly adhered to it, swiftly arresting bleeding and facilitating wound healing. Cytocompatibility tests, hemolysis tests, antibacterial assays, and coagulation assays demonstrated excellent biocompatibility, antibacterial, and hemostatic properties of HGO‐C. Finally, the in vivo experiments, including a liver hemorrhage assay and a wound healing assay, unequivocally showed the rapid hemostatic and enhanced wound healing capabilities of HGO‐C. Consequently, these distinctive hydrogel patches, derived from natural polymers and characterized by their asymmetric adhesion properties, may have great potential for real‐life usage in clinical patients.

show abstract

Self-absorbing multilayer skin-like composite with Phyllostachys nigra polysaccharides promotes wound healing

Zhao,

Qi,

et al. 2024

Adv Compos Hybrid Mater

View full text Add to dashboard Cite

A wet-adhesive carboxymethylated yeast β-glucan sponge with radical scavenging, bacteriostasis and anti-inflammatory functions for rapid hemostasis

Cited by 17 publications

References 43 publications

Recent Advances in Topical Hemostatic Materials

Recent Advances in Topical Hemostatic Materials

Novel Natural Polymer‐Based Hydrogel Patches with Janus Asymmetric‐Adhesion for Emergency Hemostasis and Wound Healing

Self-absorbing multilayer skin-like composite with Phyllostachys nigra polysaccharides promotes wound healing

Contact Info

Product

Resources

About