A wireless and sensitive detection of octachlorostyrene using modified AuNPs as signal-amplifying tags

Chen, Lan; Li, Jiezhen; Tran.T, ThanhThuy; Zhou, Liping; Huang, Chen'an; Yuan, Lijuan; Cai, Qingyun

doi:10.1016/j.bios.2013.08.026

Cited by 9 publications

(6 citation statements)

References 28 publications

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“…Besides, the ME biosensor method is comparatively fast, requiring only several minutes whereas TaqMan-based quantitative real-time PCR (qPCR) requires 2–3 h, and its operation principle is relatively easy 40 . Furthermore, previous researches 19 , 27 , 40 have also demonstrated the significant advantages in terms of sensitivity, cost and ease of use of the ME biosensor methodology. For the detection of CSFV E2 antibody, various published methods are summarized in Table 1 , showing the superior performance of our biosensor.…”

Section: Resultsmentioning

confidence: 99%

“… From equation ( 2 ), we can conclude that an extra mass load on the sensor surface leads to a decrease of f 0 . As the resonance frequency is sensitive to the mass change, the sensor modified with a chemically or biologically sensitive polymer can be designed for detection of several bacteria and protein, such as Bacillus anthracis spores 24 , 25 , Salmonella typhimurium 26 , octachlorostyrene 27 . As well known, signal amplification is a critical challenge to the biological detection.…”

Section: Introductionmentioning

confidence: 99%

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A magnetoelastic biosensor based on E2 glycoprotein for wireless detection of classical swine fever virus E2 antibody

Guo

Sang

Guo

et al. 2017

Sci Rep

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A wireless magnetoelastic (ME) biosensor immobilized with E2 glycoprotein was first developed to detect classical swine fever virus (CSFV) E2 antibody. The detection principle is that a sandwich complex of CSFV E2 – rabbit anti-CSFV E2 antibody – alkaline phosphatase (AP) conjugated goat anti-rabbit IgG formed on the ME sensor surface, with biocatalytic precipitation used to amplify the mass change of antigen–antibody specific binding reaction, induces a significant change in resonance frequency of the biosensor. Due to its magnetostrictive feature, the resonance vibrations and resonance frequency can be actuated and wirelessly monitored through magnetic fields. The experimental results show that resonance frequency shift increases with the augmentation of the CSFV E2 antibody concentration. Scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS) and fluorescence microscopy analysis proved that the modification and detection process were successful. The biosensor shows a linear response to the logarithm of CSFV E2 antibody concentrations ranging from 5 ng/mL to 10 μg/mL, with a detection limit (LOD) of 2.466 ng/mL and the sensitivity of 56.2 Hz/μg·mL−1. The study provides a low-cost yet highly-sensitive and wireless method for selective detection of CSFV E2 antibody.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A magnetoelastic biosensor based on E2 glycoprotein for wireless detection of classical swine fever virus E2 antibody

Guo

Sang

Guo

et al. 2017

Sci Rep

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“…The resonance frequency of WMS was measured by a magnetoelastic sensor reader which was interfaced to a computer via a RS232 port for data display and storage [12][13][14][15] (Fig. S1, see Supplementary data), and measurement resolution is approximately 0.5 Hz.…”

Section: Apparatusmentioning

confidence: 99%

“…S1 (see Supplementary data). The sensor platform is made of a magnetoelastic material of amorphous ferromagnetic alloys [12][13][14][15], which possesses the property of elongating or contracting along the direction of an applied external magnetic field. In the presence of a time-varying magnetic field, the sensor resonator undergoes a corresponding change of oscillating shape, giving rise to a mechanical vibration at a certain resonance frequency.…”

Section: Design Strategy and Wireless Sensing Principlementioning

confidence: 99%

“…Fortunately, the wireless magnetoelastic sensors (WMS) have been developed for detecting Staphylococcus [12], Escherichia coli O157:H7 [13], breast cancer cell [14], and so on. These sensors have some noteworthy advantages of being low cost, remote query and high sensitivity [15][16][17]. Nanomaterials such as graphene oxide (GO) have attracted much interest recently [18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

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Streptavidin and gold nanoparticles-based dual signal amplification for sensitive magnetoelastic sensing of mercury using a specific aptamer probe

Huang

Yin

Wang

et al. 2016

Sensors and Actuators B: Chemical

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A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

et al. 2020

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fever with or without chills, chest tightness, dry cough, and shortness of breath, while developing patchy to diffuse infiltration of the lungs, as shown radiographically in Figure 1. Identifying and monitoring SARS-CoV-2 infection has become crucially important. A recent projection of the transmission dynamics of SARS-CoV-2 [2] showed that longitudinal serological studies are desperately needed to determine the extent and duration of immunity to SARS-CoV-2. Even in the event of apparent elimination, maintenance of SARS-CoV-2 surveillance is still needed because of a possible resurgence of contagion. In the past, notable viruses have emerged suddenly from obscurity or anonymity, provoking concern from the point of view of immunology regarding their sustained epidemic transmission in naive human populations. More than 70% of these infections have been zoonotic, entering either directly from wild animal reservoirs or indirectly via an intermediate domestic animal host. [3] Ebola virus, avian influenza, human immunodeficiency virus (HIV), and SARS are all examples of zoonoses that have emerged from wild animals, presenting an increasingly serious threat to human health and economies worldwide. Figure 2 shows the trend in the number of people infected with SARS-CoV-2. [4] The spread of the severe acute respiratory syndrome coronavirus has changed the lives of people around the world with a huge impact on economies and societies. The development of wearable sensors that can continuously monitor the environment for viruses may become an important research area. Here, the state of the art of research on biosensor materials for virus detection is reviewed. A general description of the principles for virus detection is included, along with a critique of the experimental work dedicated to various virus sensors, and a summary of their detection limitations. The piezoelectric sensors used for the detection of human papilloma, vaccinia, dengue, Ebola, influenza A, human immunodeficiency, and hepatitis B viruses are examined in the first section; then the second part deals with magnetostrictive sensors for the detection of bacterial spores, proteins, and classical swine fever. In addition, progress related to early detection of COVID-19 (coronavirus disease 2019) is discussed in the final section, where remaining challenges in the field are also identified. It is believed that this review will guide material researchers in their future work of developing smart biosensors, which can further improve detection sensitivity in monitoring currently known and future virus threats.

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A wireless and sensitive detection of octachlorostyrene using modified AuNPs as signal-amplifying tags

Cited by 9 publications

References 28 publications

A magnetoelastic biosensor based on E2 glycoprotein for wireless detection of classical swine fever virus E2 antibody

A magnetoelastic biosensor based on E2 glycoprotein for wireless detection of classical swine fever virus E2 antibody

Streptavidin and gold nanoparticles-based dual signal amplification for sensitive magnetoelastic sensing of mercury using a specific aptamer probe

A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses

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