A Working Model of Protein Synthesis Using Lego<sup>TM</sup>Building Blocks

Templin, Mark; Fetters, Marcia

doi:10.1662/0002-7685(2002)064[0673:awmops]2.0.co;2

Cited by 10 publications

(2 citation statements)

References 7 publications

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“…Building block models have been used as interactive aids in STEM education, such as by modeling chemical structures or by simulating protein synthesis [5,39]. Even though building block structures can only coarsely approximate arbitrary objects, their familiarity, tangibility, and ease-of-use makes them appealing and versatile modeling tools.…”

Section: Potential Usesmentioning

confidence: 99%

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Miller

White

Charbonneau

et al. 2012

IEEE Trans. Visual. Comput. Graphics

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Fig. 1. An overhead view of our system in action. A depth camera observes the creation of a physical structure made of building blocks. Our system continuously updates a virtual model of the structure as the user adds and removes pieces.Abstract-We present a prototype system for interactive construction and modification of 3D physical models using building blocks. Our system uses a depth sensing camera and a novel algorithm for acquiring and tracking the physical models. The algorithm, Lattice-First, is based on the fact that building block structures can be arranged in a 3D point lattice where the smallest block unit is a basis in which to derive all the pieces of the model. The algorithm also makes it possible for users to interact naturally with the physical model as it is acquired, using their bare hands to add and remove pieces. We present the details of our algorithm, along with examples of the models we can acquire using the interactive system. We also show the results of an experiment where participants modify a block structure in the absence of visual feedback. Finally, we discuss two proof-of-concept applications: a collaborative guided assembly system where one user is interactively guided to build a structure based on another user's design, and a game where the player must build a structure that matches an on-screen silhouette.Index Terms-Interactive physical model building, 3D model acquisition, object tracking, depth cameras, building block structures.

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Section: Potential Usesmentioning

confidence: 99%

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Miller

White

Charbonneau

et al. 2012

IEEE Trans. Visual. Comput. Graphics

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“…Although several laboratory exercises are based on simulating protein synthesis using beads or models (Rode 1995;Souter and Stitt 1995;Sprehn 1993;Templin and Fetters 2002), research suggests that most proteins are synthesized in a modular fashion using specific combinations of structural and functional domains. Our experience indicates that understanding protein domain structure and function is difficult for many students.…”

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confidence: 99%

Modeling Protein Domain Function

Baker

Jones

Hull

2007

Science Activities: Classroom Projects and Curriculum Ideas

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This simple but effective laboratory exercise helps students understand the concept of protein domain function. They use foam beads, Styrofoam craft balls, and pipe cleaners to explore how domains within protein active sites interact to form a functional protein. The activity allows students to gain content mastery and an understanding of the vital role of proteins within cells. The exercise also enables teachers to assess student performance on several levels. roteins serve vital roles within cells. Enzymes catalyze the reactions in metabolism, structural proteins give cells and tissues their shape, and transport proteins move nutrients around the body. To perform these important functions, proteins must be folded correctly. Proteins are composed of amino acids. Each amino acid is linked to a neighboring amino acid by a covalent bond known as a peptide. The peptide bond is rigid and limits the way an amino acid chain can fold, giving each protein its characteristic shape or structure.Research has shown that side chains are what make each amino acid unique and result in each protein folding differ-WILLIAM P. BAKER is an associate professor and coordinator of the Biomedical Sciences Program at

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Effect of bead and illustrations models on high school students' achievement in molecular genetics

Rotbain

Marbach‐Ad

Stavy

2006

J. Res. Sci. Teach.

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Our main goal in this study was to explore whether the use of models in molecular genetics instruction in high school can contribute to students' understanding of concepts and processes in genetics. Three comparable groups of 11th and 12th graders participated: The control group (116 students) was taught in the traditional lecture format, while the others received instructions which integrated a bead model (71 students), or an illustration model (71 students). Similar instructions and the same guiding questions accompanied the two models. We used three instruments: a multiple‐choice and an open‐ended written questionnaire, as well as personal interviews. Five of the multiple‐choice questions were also given to students before receiving their genetics instruction (pretest). We found that students who used one of the two types of models improved their knowledge in molecular genetics compared to the control group. However, the open‐ended questions revealed that bead model activity was significantly more effective than illustration activity. On the basis of these findings we conclude that, though it is advisable to use a three‐dimensional model, such as the bead model, engaging students in activities with illustrations can still improve their achievement in comparison to traditional instruction. © 2006 Wiley Periodicals, Inc. J Res Sci Teach 43: 500–529, 2006

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A Working Model of Protein Synthesis Using Lego^TMBuilding Blocks

Cited by 10 publications

References 7 publications

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Modeling Protein Domain Function

Effect of bead and illustrations models on high school students' achievement in molecular genetics

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A Working Model of Protein Synthesis Using LegoTMBuilding Blocks

Cited by 10 publications

References 7 publications

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Interactive 3D Model Acquisition and Tracking of Building Block Structures

Modeling Protein Domain Function

Effect of bead and illustrations models on high school students' achievement in molecular genetics

Contact Info

Product

Resources

About

A Working Model of Protein Synthesis Using Lego^TMBuilding Blocks