A WS₂-gold nanoparticle heterostructure-based novel SERS platform for the rapid identification of antibiotic-resistant pathogens

Abstract

The emergence of antibiotic-resistant bacteria is the biggest threat to our society.

Highly Suppressed Dark Current and Fast Photoresponse from Au Nanoparticle-Embedded, Si/Au/WS2 Quantum-Dot-Based, Self-Biased Schottky Photodetectors

“…Interestingly, in the latter case, there was a ∼10-fold enhancement in the intensity of the A 1g mode of WS 2 QDs owing to the surface-enhanced Raman spectroscopy (SERS) effect caused by the Au NPs. Au NPs are well-known SERS materials that enhance the Raman signal via electromagnetic field enhancement . The Raman spectra for both the cases were deconvoluted, and a stacked plot is displayed in Figure b.…”

“…In addition to manipulating optical properties, metal nanostructures are also used as efficient surface-enhanced Raman scattering (SERS) substrates. Pramanik et al reported a study on the integration of Au nanoparticles (NPs) with WS 2 nanosheets as a novel SERS platform for detecting antibiotic-resistant bacteria . To the best of our knowledge, the effect of Au NPs on the optical properties of WS 2 QDs is not yet explored.…”

“…Pramanik et al reported a study on the integration of Au nanoparticles (NPs) with WS 2 nanosheets as a novel SERS platform for detecting antibioticresistant bacteria. 38 To the best of our knowledge, the effect of Au NPs on the optical properties of WS 2 QDs is not yet explored. Further, the integration of WS 2 QDs with Au NPs grown by a physical deposition method is yet to be explored, which is most suitable for the large-scale fabrication of highperformance devices.…”

Recent Advances in the Detection of Antibiotic and Multi-Drug Resistant Salmonella: An Update

“…With the advent of cheaper, highly conductive 2D dimensional nanomaterials, such as graphene and molybdenum disulfide, interest in the sensing applications of mature nanomaterials like CNT and nanoAg has begun to wane. Recent work [ 87 ] employing a 2D–0D heterostructure-based SERS platform in the rapid detection of Salmonella DT104 utilized an alternative transduction element consisting of a (2D) WS2 transition metal dichalcogenide (TMD) and a (0D) plasmonic gold nanoparticulate (GNPs) lattice. The authors showed the device could rapidly discriminate multidrug resistant Salmonella DT104 from S. Typhi using AST and Augmentin antibiotics up to concentrations of 100 CFU/mL.…”

“…An SEM image showing the damaged walls of Salmonella Typhi ( d ) after treatment with the Augmentin antibiotic. Figure modified with permission from [ 87 ]. (Copyright 2020, American Chemical Society).…”