A xanthone from Garcinia mangostana

Sen, A. K.; Sarkar, Kamal; Mazumder, Pronobesh C.; Banerji, Nilima; Uusvuori, Raimo; Haset, Tapio A.

doi:10.1016/s0031-9422(00)82235-9

Cited by 55 publications

(4 citation statements)

References 16 publications

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“…The known compounds were identified as garcinones C [8] and D [9] ( 3 and 4 ), gartanin [10,11] ( 5 ), xanthone I [12] ( 6 ), and γ-mangostin [13] ( 7 ), respectively, by comparison of their physical and spectroscopic data with those reported previously.…”

Section: Resultsmentioning

confidence: 99%

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

Huang

Chen

et al. 2014

Molecules

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Bioassay-guided fractionation of an ethanol extract of the pericarps of Garcinia mangostana led to the isolation of two new prenylated xanthones, named 1,3,7-trihydroxy-2-(3-methyl-2-butenyl)-8-(3-hydroxy-3-methylbutyl)-xanthone (1) and 1,3,8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl)-xanthone (2), together with the five known compounds garcinones C (3) and D (4), gartanin (5), xanthone I (6), and γ-mangostin (7). Their structures were elucidated primarily based on MS and NMR data. Compounds 1-7 showed significant cytotoxic activities against various human cancer cell lines.

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Section: Resultsmentioning

confidence: 99%

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

Huang

Chen

et al. 2014

Molecules

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“…The fruits of G. mangostana show good taste hence it is called as "queen of fruits" and it contains a rich source of phenolic compounds such as xanthones, condensed tannins, and anthocyanins 2,3 . In Ayurvedic medicine, the pericarp of mangostan-fruit has been widely used against inflammation, diarrhea, cholera, and dysentery 4,5 .Nanotechnology is an extremely powerful emerging technology that is expected to have a substantial impact on technology now and in the future 6 . Before 100 years, Michael Faraday reported the colloidal form of gold nanoparticles.…”

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Dyeing of cotton fabric materials with biogenic gold nanoparticles

Sivakavinesan

Vanaja

Annadurai

2021

Sci Rep

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The present work aimed at synthesizing gold nanoparticles in a biological method employing fruit peel waste dumped in the environment. The peels of Garcinia mangostana (Mangostan), were collected from the nearby tourist spot during the season. The collected fruit peels were washed, dried, powder and extracted by using boiling water and acetone. The precipitated extract was dried and powdered for further use. The dried and powdered peel extract was added to the gold solution and boiled to 80 °C and the color change is observed. The color change indicates the completion of the synthesis of gold nanoparticles. The effect of pH, gold ion concentration, peel extract powder concentration, and the temperature was tested by varying the parameters. The biosynthesized nanoparticles were characterized using the UV–Vis spectrophotometer to identify the surface plasmon resonance peaks corresponding to gold nanoparticles. The bio-moieties responsible for the synthesis of gold nanoparticles were identified using the Fourier Transform Infra-Red Spectroscopy. The crystalline nature was detected by using an X-Ray Diffractometer. Atomic Force Microscope viewed the 3D surface image of the gold nanoparticle. The shape and morphology of the nanoparticle were identified by using a Field Emission Scanning Electron Microscope. The active compounds for gold nanoparticle synthesis were identified using Gas Chromatography-Mass Spectrometry. The gold nanoparticle was synthesized in various colors and used for dyeing cotton fabrics. The dyed cotton materials were exposed to various stress conditions to determine the color fastening.

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“…1,3,6,7-tetrahydroxyxanthone (GT21) [126], 1,3,5,6-tetrahydroxyxanthone (GT22) [126], nitidaxanthone (GT23) [118], cylindroxanthone B (GT24) [13], cylindroxanthone A (GT25) [13], 9-hydroxycalabaxanthone (GT26) [144], macluraxanthone (GT27) [145],…”

Section: Resultsmentioning

confidence: 99%

Chemical constituents from the stems of garcinia cylindrocarpa and the stem bark of garcinia picrorhiza and garcinia tetrandra

Sukandar

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Aiming to discover novel bioactive secondary metabolites from genus Garcinia, we performed phytochemical and biological investigations of three�Garcinia�species collected from Indonesia. A series of chromatographic techniques and spectroscopic data analysis�were used to isolate and characterize�the Garcinia phytochemicals. The cytotoxicity of the isolated compounds was�evaluated against five human cancer cell lines�(HeLa S3, Hep G2, HT-29, MCF-7, and KB) using MTT assay. Four new xanthones, cylindroxanthones DG, and two new biphenyls, cylindrobiphenyls A and B, together with 28 known compounds were successfully isolated from�G. cylindrocarpa stems. From the stem bark of G. tetrandra, nine new xanthones, tetrandraxanthones AI, were identified along with 22 previously described analogues. Eight new polyprenylated benzoylphloroglucinols (PPBPs), picrorhizones AH, and four known analogues were reported from the stem bark of�G. picrorhiza. Among the tested compounds, 9-hydroxycalabaxanthone showed significant cytotoxicity against five human cancer cell lines�with IC50 values in the range of 1.63.4 ?M, while 2-deprenylrheediaxanthone B and picrorhizone F were active against four cancer cells, except HT-29, with IC50 values ranging from 2.2 to 9.4 ?M.

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A xanthone from Garcinia mangostana

Cited by 55 publications

References 16 publications

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

Dyeing of cotton fabric materials with biogenic gold nanoparticles

Chemical constituents from the stems of garcinia cylindrocarpa and the stem bark of garcinia picrorhiza and garcinia tetrandra

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