A Young Woman With Sudden Urinary Retention and Sensory Deficits

Patterson, Susan; Jafri, Kashif; Narvid, Jared; Margaretten, Mary

doi:10.1002/acr.23473

Cited by 3 publications

(1 citation statement)

References 42 publications

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“…5,6 We further identified four more cases in the literature where NMOSD was the first manifestation of SLE. 7–10 The salient features of these six cases where NMOSD was the first manifestation of SLE are summarized in Table 1. All these six patients were women, all fulfilled the clinical and imaging criteria for NMOSD.…”

Section: Discussionmentioning

confidence: 99%

Neuromyelitis optica spectrum disorder and systemic lupus erythematosus

Thabah

Dineshbabu

Pranov

et al. 2019

Lupus

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Neuromyelitis optica spectrum disorder is an inflammatory syndrome that is associated with many autoimmune conditions. We present the case of a patient who had longitudinally extensive transverse myelitis and antibodies to aquaporin 4 IgG (AQP4-IgG). Based on presence of lymphopenia, further workup revealed strong ANA positivity, anti-Sm antibodies, and low serum complements suggesting presence of systemic lupus erythematosus. The patient promptly responded to intravenous pulse methylprednisolone and five sessions of plasma exchange. At 1 year, she is on maintenance treatment with low dose prednisolone, azathioprine, and hydroxychloroquine, she has had no relapse and no other clinical features of lupus. This case is an illustration that neuromyelitis optica spectrum disorder can be the first manifestation of systemic lupus erythematosus.

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