2018
DOI: 10.1093/jcag/gwy009.215
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A215 Quality Indicators of Upper and Lower Digestive Endoscopy in Children: A Systematic Review and Meta-Analysis

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“…Vote: strongly agree, 66.7%; agree, 29.2%; uncertain, 4.1% Key evidence: Despite numerous current pediatric consensus statements that recommend routine tissue sampling even in the absence of visible endoscopic abnormalities in all children undergoing upper endoscopy and ileocolonoscopy to improve the likelihood of detecting disease, if present, the quality of evidence to support this practice is low and indirect (3,5,(89)(90)(91). Although pediatric studies have been generally retrospective single-center studies, their findings have consistently suggested that performance of both upper gastrointestinal endoscopy and ileocolonoscopy with biopsies increases diagnostic yield during evaluation for suspicion of inflammatory bowel disease, and may be important in disease differentiation (89,(92)(93)(94)(95)(96)(97)(98). For example, evidence-based international guidelines related to Helicobacter pylori (91), celiac disease (90), eosinophilic esophagitis (99) and inflammatory bowel disease (100) all outline the sites and number of biopsies recommended for pediatric endoscopy.…”
Section: 3%mentioning
confidence: 99%
“…Vote: strongly agree, 66.7%; agree, 29.2%; uncertain, 4.1% Key evidence: Despite numerous current pediatric consensus statements that recommend routine tissue sampling even in the absence of visible endoscopic abnormalities in all children undergoing upper endoscopy and ileocolonoscopy to improve the likelihood of detecting disease, if present, the quality of evidence to support this practice is low and indirect (3,5,(89)(90)(91). Although pediatric studies have been generally retrospective single-center studies, their findings have consistently suggested that performance of both upper gastrointestinal endoscopy and ileocolonoscopy with biopsies increases diagnostic yield during evaluation for suspicion of inflammatory bowel disease, and may be important in disease differentiation (89,(92)(93)(94)(95)(96)(97)(98). For example, evidence-based international guidelines related to Helicobacter pylori (91), celiac disease (90), eosinophilic esophagitis (99) and inflammatory bowel disease (100) all outline the sites and number of biopsies recommended for pediatric endoscopy.…”
Section: 3%mentioning
confidence: 99%