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Abstract

The aspirin-exacerbated respiratory disease (AERD) comprises a set of signs and symptoms that mainly involve the upper and lower airway after consumption of inhibitors of the cyclooxygenase enzyme (COX). An adequate diagnosis is essential confirmed by provocation tests; as well as, educating the patient in the use or elimination of the different NSAIDs, and the use of an analgesic alternative. Its management includes pharmacological treatment for asthma control, surgical procedures for the control of nasal polyps, and desensitization with aspirin in selected individuals. Here, we present a successful case of desensitization to AINES. Following a nine-hour protocol, in a 56-year-old patient diagnosed with AERD; Tolerance to NSAIDs and symptom control was successfully achieved.