Recently, low back pain (LBP) has been a major contributor to disability worldwide. Chronic LBP affects 80% of the population at some point. The incidence of LBP is on the rise, especially among the elderly, and it is more common in men than in women. The different aspects of one’s life, such as a history of mental illness, being overweight, smoking, not getting enough exercise, getting older, and leading a sedentary lifestyle, all increase the likelihood of developing LBP. According to research, there are a number of causes and contributing factors that add up to a hefty price tag for disabled people. Functional disability in chronic LBP can be caused in part by causes other than the disease itself, such as psychological and professional variables, and can put restrictions on one’s personal life, work life, and family life. According to a recent study, more than 80% of those with a functional disability were classified as having a moderate-to-severe impairment. Therefore, we have proposed this review to clarify the appropriate assessment and interventional modalities for LBP and reduce disability. The diagnosis of LBP may need physical examination as well as imaging procedures to rule out the possibility of other ailments, such as broken bones. There is more than one technique to treat the underlying causes of LBP. Interventions include several modalities, including medication, physical therapy, manual therapy, injections, and surgery. In terms of pain treatment, we could choose between over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) and prescribed drugs. Back spasms can be treated with other medications that relax the muscles in the back. Physiotherapy can help an individual build up the core muscles that protect the spine. Physical therapy can help individuals to stay injury-free by doing more than just increasing the range of motion. Tense muscles can be relaxed, pain can be lessened, and posture and alignment can be enhanced through a series of sessions.