2014
DOI: 10.1136/annrheumdis-2014-eular.3582
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AB0554 Expression of Serum B Cell Activating Factor from the Tumour Necrosis Factor Family (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Systemic Lupus Erythematosus: Relationship with Disease Activity

Abstract: Background The B lymphocyte stimulator signaling pathway by BAFF and its homologue APRIL has an important role in the selection, maturation and survival of B cells and plays a significant role in the pathogenesis of systemic lupus erythematosus (SLE). Objectives The aim of the study is to evaluate BAFF and APRIL in patients with SLE. Methods The 30 pts (80% female, age 31,0 [28,0-45,0 years] (mediana [interquartile range 25%>75%])) with SLE (ACR criteria, 1982) and 27 controls (93% female without any rheum… Show more

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