AB0706 Capillaroscopy: a useful tool for primary raynaud identification

Abstract

Background The identification of individuals with primary Raynaud’s likely to develop scleroderma or other connective tissue diseases is of great importance in order to have an early control and therapeutic management of the disease, with great influence on the patient’s prognosis. The most appropriate methodology for this would be the capillaroscopy, as it is an affordable, non-invasive and easy to use method. Objectives Evaluate the correlation between clinical diagnosis and capillaroscopic pattern in patients with Raynaud’s phenomenon both primary and secondary. Methods We performed a descriptive observational study comprising 116 capillaroscopies performed in the H.U.P. La Fe in 2012. All were conducted on patients with Raynaud’s phenomenon both primary and secondary. Rheumatologists ignored the clinical diagnosis for each case and based on observed characteristics a capillaroscopic pattern was assigned to each patient. We performed a biostatistical analysis using multinomial logistic regression model in order to estimate the likelihood of each diagnosis based on a given capillaroscopic pattern. Results The results obtained in the capillaroscopies are: heterogeneous capillary disposition (30%); visible venous plexus (44%) maintained capillary density (78%), decreased (15%), greatly decreased (7%); elongated capillary morphology (24%), lack of dilatation (22%), isolated dilatation (40%), diffuse dilatation (38%); existence of megacapillaries (28%); existence of bleeding (56%), presence of avascular areas (8%), absence of windings (10%), presence of grade I tortuosities (29%), grade II (38%), grade III (22%); angiogenesis (47%). According to these results the patients were classified according to the capillaroscopic pattern and clinical diagnosis. See Table 1. Conclusions Our results showed that a high percentage of cases with a regular capillaroscopic pattern had a high probability of presenting/displaying Primary Raynaud’s diagnosis. Thus, capillaroscopy could be useful in primary Raynaud’s discrimination based on the pattern found. Disclosure of Interest None Declared