Ab0714 balance and Falls in Axial Spondyloarthritis: A Cross Sectional Study

Abstract

Background:Spondyloarthritis (SpA) patients may suffer of balance loss predisposing them to falls.Objectives:To study balance impairment and falls in SpA patients and its association with clinical and epidemiological variables, disease activity, functional and metrology indexes.Methods:Cross sectional study of 55 SpA patients with axial disease. Clinical and epidemiological were collected from the charts. Balance was accessed by Berg Balance Scale(BBS). The following instruments were applied: aSDAS(Ankylosing Spondylitis Disease activity Score)-ESR, aSDAS-CRP, BASDAI(Bath ankylosing Spondylitis Disease activity index), BASFI(Bath ankylosing Spondylitis Functional index), BASMI(Bath ankylosing Spondylitis Metrology index) and aSQoL (Ankylosing spondylitis quality of life questionnaire). The number of falls in the last year was collected.Results:In this sample, 30.9% had high risk of falls by the BBS and 25.4% recalled having at least one fall in the last years. The BBS values were lower in those with white ethnic background(p=0.01); and smokers(p=0.03) and with HLA-B27(p=0.03) and correlated inversely with BASDAI(rho=-0.28), aSDAS-ESR(rho=-0.32) and aSDAS-CRP(rho=-0.33), BASFI(rho=-0.71,p<0.0001), BASMI(rho=-0.80; p<0.0001), aSQoL(rho=-0.57;p<0.001) and age(rho=-0.50;p<0.001). Multivariated analysis showed that BASFI and BASMI were independently associated with BBS(p=0.02 and 0.0001 respectively). Patients with falls had lower BBS (p=0.03) and loss of balance correlated with impairment of the quality of life(rho=-0.56;p<0.001).Conclusion:Balance is impaired in 1/3 of SpA patients and the BBS is associated mainly with functional and metrology indexes, showing that patients with severe cumulative damage are more affected.References[1] - Pompeu JE, Romano RS, Pompeu SM, Lima SM. Static and dynamic balance in subjects with ankylosing spondylitis: literature review. Rev Bras Reumatol. 2012; 52:409-16.[2] - Sawacha Z, Carraro E, Del Din S, Guiotto a, Bonaldo L, Punzi L, et al. Biomechanical assessment of balance and posture in subjects with ankylosing spondylitis. J. Neuroeng Rehabil. 2012; 9:63.TABLE 1- STUDY of BBS(BALANCE BERG SCALE) VALUES aCCORDING to EPIDEMIOLOGICAL, CLINICAL aND TREATMENT VARIABLESMedian BBS with the variable (IQR)Median BBS without the variable (IQR)pMale gender51(44.0-55.0)51.0(44.2-53.7)0.80White ethnic background49.0(42.5-53.0)54.0(30.2-55.0)0.01Exposed to tobacco (ex and current)46.0(41.5-54.0)52.0(46.5-55.0)0.03Bilateral sacroiliitis51.0(45.0-55.0)53.5(46.2-55.0)0.63Enthesitis50.0(38.5-55.2)51.0(44.5-55.0)0.45Dactilitis50.5(42.0-54.2)51.0(44.0-55.0)0.73Uveitis51.0(46.5-55.0)50.5(41.7-55.0)0.26Peripheral arthritis52.0(40.7-55.7)51.0(33.0-54.0)0.92HLA B27 presence52.0(44.5-55.0)48.5(39.5-51.1)0.03Anti TNF-α users50.5(45.0-54.7)52.0(39.0-55.0)0.67History of falls in the last year46.5(40.0-50.2)52.0(44.5-55.0)0.03TABLE 2- CORRELATION STUDIES of BBS (BERG BALANCE SCALE) VALUES with aGE, DISEASE DURATION, DISEASE aCTIVITY inDEXES, FUNCTIONAL aND METROLOGY inDEXES aND QUALITY of LIFERho95% confiden...

Ankylosing Spondylitis and the Risk of Hip Fractures: a Matched Cohort Study

“…On the one hand, ankylosing spondylitis and its duration are associated with an increased risk of falls. 26,27 This is likely due to an impairment of balance often seen in ankylosing spondylitis patients, which may arise due to a combination of pain, reduced mobility, and irreversible postural changes. 10,28 On the other hand, ankylosing spondylitis is associated with bone loss in both the vertebrae and the hip 12,29 , and the severity of disease is associated with decreased trabecular bone density.…”