Ab0886 incidence of Fractures in a Bariatric Surgery Cohort

Abstract

Background:Bariatric surgery is the set of surgical techniques whose objective is weight reduction, and it could have complications. One of them may be the increase in the incidence of fractures (1), secondary to nutritional defects (2), among others, that could modify bone metabolism with an increase in remodeling (3).Objectives:To carry out a retrospective observational pilot analysis of a cohort of 140 morbidly obese patients after bariatric surgery, of a total of 304, descriptive of axial and peripheral fractures, among other variables.Methods:Data were collected from the University Hospital of Fuenlabrada of a cohort of morbidly obese people who underwent bariatric surgery from 2009 to the present. Were included as variables age in years, sex, body mass index (BMI) before surgery, evolution time since surgery in years, incidence of sleep apnea syndrome (OSAS), incidence and type of fracture, osteoporotic or not, and axial or peripheral. A descriptive and frequency analysis, and a chi-square contingency table between incidence of fracture, and gender, OSAS, or childhood obesity, were performed.Results:A 48.76 years old cohort was observed, 25.7% men/74.3% women, 30.8% childhood obesity, BMI of 45.65 kg / m2, and 45% with a diagnosis of OSAS. A 15% of fractures were noted: 66.66% considered as osteoporotics (40.76% axial, 50.31% peripheral, and 8.93% of both) in a time of evolution of 5.81 years, and without relationship with gender, OSAS or childhood obesity (p = 0.7, p = 0.15, p = 0.16).Conclusion:It is a study that higlights that bariatric surgery in Fuenlabrada area is mainly performed on morbidly obese women in adulthood. There is a high rate of OSAS, and an increase in the incidence of fractures unrelated to gender, OSAS or childhood obesity, despite the fact that in the bariatric surgery protocol densitometric osteoporosis is an exclusion criterion.References:[1]Rousseau C, Jean S, Gamache P, Lebel S, Mac-Way F, Biertho L, et al. Change in fracture risk and fracture pattern after bariatric surgery: nested case-control study. BMJ. 27 july 2016;354:i3794.[2]Scibora LM. Skeletal effects of bariatric surgery: examining bone loss, potential mechanisms and clinical relevance. Diabetes Obes Metab2014;16:1204-13. doi:10.1111/dom.12363 pmid:25132010.[3]Coates PS, Fernstrom JD, Fernstrom MH, Schauer PR, Greenspan SL. Gastric bypass surgery for morbid obesity leads to an increase in bone turnover and a decrease in bone mass. J Clin Endocrinol Metab2004;89:1061-5. doi:10.1210/jc.2003-031756 pmid:15001587.Disclosure of Interests:None declared