Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates

Quint, Evelien E.; Liu, Yi; Shafaat, Omid; Ghildayal, Nidhi; Crosby, Helen; Kamireddy, Arun; Pol, Robert A.; Orandi, Babak J.; Segev, Dorry L.; Weiss, Clifford R.; McAdams-DeMarco, Mara A.

doi:10.1016/j.ajt.2023.11.002

American Journal of Transplantation

2024

DOI: 10.1016/j.ajt.2023.11.002

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Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates

Evelien E. Quint,

Yi Liu,

Omid Shafaat

et al.

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2024

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Cited by 2 publications

References 60 publications

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Nutritional status and changes in muscle and adipose tissue determined by computed tomography as predictors of mortality in hospitalized patients

Soares,

Burgos

et al. 2024

Radiol Bras

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The aim of the present study was to investigate whether nutritional status and changes in muscle and adipose tissue determined by computed tomography are predictors of mortality in hospitalized patients. This was a prospective cohort study involving patients ≥ 20 years of age hospitalized in a public hospital. Sociodemographic and clinical variables were collected from electronic medical records. Nutritional variables were determined. All patients were followed prospectively until the hospital outcome, which could be discharge or death. Body composition was defined from computed tomography images, with the identification of myopenia, myosteatosis, and myopenic obesity. The sample comprised 542 patients. The mortality rate was 10.7% (95% CI: 6.4-15.0%). The independent predictors of mortality were malnutrition, assessed with the subjective global assessment (hazard ratio: 4.18; 95% CI: 1.01-17.22; p = 0.047), and myopenic obesity (hazard ratio: 2.82; 95% CI: 1.11-7.20; p = 0.029). The findings of the present study add to the limited evidence in the literature that body composition is associated with outcomes in hospitalized patients.

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Nutritional status and changes in muscle and adipose tissue determined by computed tomography as predictors of mortality in hospitalized patients

Soares,

Burgos

et al. 2024

Radiol Bras

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Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease

2024

Adv Geriatr Med Res

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Sarcopenia, defined as a loss of muscle mass and function, is a physiologic factor that has been implicated as a predictor of adverse postoperative outcomes in many older adult populations. However, data related to sarcopenia in older adults with inflammatory bowel disease (IBD) remain limited. Older adults with IBD are particularly vulnerable to adverse postoperative outcomes, in part, due to muscle depletion from systemic inflammation, malnutrition, and reduced physical activity. However, few patients undergo routine muscle evaluation as a part of preoperative assessment. Moreover, cut-off values for measures of sarcopenia in the literature are modeled after non-IBD populations. The lack of standardized measures and values for sarcopenia in the IBD patient population has led to heterogenous findings and a paucity of preoperative risk stratification tools. Therefore, we aim to explore the scope of sarcopenia as a preoperative risk stratification tool among older adults with IBD.

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Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates

Cited by 2 publications

References 60 publications

Nutritional status and changes in muscle and adipose tissue determined by computed tomography as predictors of mortality in hospitalized patients

Nutritional status and changes in muscle and adipose tissue determined by computed tomography as predictors of mortality in hospitalized patients

Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease

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