Abdominal obesity is associated with arterial stiffness in middle-aged adults

Strasser, Barbara; Arvandi, Marjan; Pasha, Evan; Haley, Andreana P.; Stanforth, Philip R.; Tanaka, Hirofumi

doi:10.1016/j.numecd.2015.01.002

Cited by 116 publications

(87 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4 Hypertension, 28 diabetes, 5 dyslipidemia 29 and obesity 30 are pointed out as potential promoters of increased arterial stiffness. Some studies have argued that African ancestry would be associated with greater arterial stiffness.…”

Section: Determinants Of Arterial Stiffnessmentioning

confidence: 99%

Arterial Stiffness: Pathophysiological and Genetic Aspects

Alvim

Santos

Bortolotto

et al. 2017

International Journal of Cardiovascular Sciences

View full text Add to dashboard Cite

Cardiovascular diseases (CVD) are the main cause of mortality and it represents a significant percentage of hospitalizations. In the scenario of minimization of costs of the health system, methods that identify subclinical CVD would be important. Some guidelines include the measures of aortic stiffness and intima-media thickness of the carotid artery as methods to identify subclinical CVD in hypertensive patients. The pulse wave velocity (PWV) is the gold standard for the evaluation of arterial stiffness. In this review, we report the pathophysiology, the determinants of arterial stiffness, and justify its inclusion in the assessment of hypertensive patient due its direct association with cardiovascular risk, as show in the I Diretriz Brasileira de Prevenção Cardiovascular. In addition, we raised the main genetic studies of this phenotype, due to its complexity, can be modulated by dozens of genes. However, a better understanding of the relationship genetic-arterial stiffness and, even an intervention based on genotypes, should be achieved in future studies.

show abstract

Section: Determinants Of Arterial Stiffnessmentioning

confidence: 99%

Arterial Stiffness: Pathophysiological and Genetic Aspects

Alvim

Santos

Bortolotto

et al. 2017

International Journal of Cardiovascular Sciences

View full text Add to dashboard Cite

show abstract

“…Some studies showed a positive correlation of waist circumference (WC) and waist/height ratio (WHtR) to PWV and carotid IMT (ref. 66,67 ). In Arners' study the visceral adipocyte volume, not number, was strongly and positively correlated with PWV, explaining 20% of the inter-individual variations in this parameter.…”

Section: Metabolic Syndrome and Obesitymentioning

confidence: 99%

Pulse wave analysis and diabetes mellitus. A systematic review

Gajdova

Karásek

Goldmannová

et al. 2017

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

Cardiovascular (CV) disease is the primary cause of death in diabetic patients and one of the explanations may be increased arterial stiffness. Arterial stiffness assessment using pulse wave analysis, is a predictive factor of CV events. The aim of this paper is to review the current knowledge of relations between diabetes mellitus and pulse wave analysis. A MEDLINE search was performed to retrieve both original and review articles addressing the relations and influences on arterial stiffness in diabetics. Pulse wave analysis is considered as a gold standard in CV risk evaluation for patients at risk, especially diabetics. Arterial stiffness assessment may be helpful for choosing more aggressive diagnostic and therapeutic strategies, particularly in younger patients to reduce the incidence of CV disease in these patients.

show abstract

“…4), arterial stiffness, and overall poor cardiovascular health (ref. 5). In addition, analyses of interventions that increase physical activity and restrict caloric intake show that reductions in VAT, not SAT, mediate improvement in cardiometabolic risk factors such as triglyceride levels, cardiorespiratory fitness (ref.…”

Section: Introductionmentioning

confidence: 99%

Associations between physical activity and BMI, body fatness, and visceral adiposity in overweight or obese Latino and non-Latino adults

et al. 2017

View full text Add to dashboard Cite

Background/Objectives Although several studies have reported associations between moderate to vigorous physical activity (MVPA), body fatness, and visceral adipose tissue (VAT), the extent to which associations differ among Latinos and non-Latinos remains unclear. The present study evaluated the associations between body composition and MVPA in Latino and non-Latino adults. Subjects/Methods An exploratory, cross-sectional analysis was conducted using baseline data collected from 298 overweight adults enrolled in a 12-month randomized controlled trial that tested the efficacy of text messaging to improve weight loss. MVPA, body fatness and VAT were assessed by waist-worn accelerometry, DXA, and DXA-derived software (GE CoreScan GE, Madison, WI) respectively. Participants with less than 5 days of accelerometry data or missing DXA data were excluded; 236 participants had complete data. Multivariable linear regression assessed associations between body composition and MVPA per day, defined as time in MVPA, bouts of MVPA (time per bout ≥10 min), non-bouts of MVPA (time per bout <10 min), and meeting the 150-minute MVPA guideline. The modifying influence of ethnicity was modeled with a multiplicative interaction term. Results The interaction between ethnicity and MVPA in predicting percent body fat was significant (p = 0.01, 95% CI [0.58, 4.43]) such that a given increase in MVPA was associated with a greater decline in total body fat in non-Latinos compared to Latinos (adjusted for age, sex and accelerometer wear time). There was no interaction between ethnicity and MVPA in predicting VAT (g) (p = 0.78, 95% CI [−205.74, 273.17]) and BMI (p = 0.18, 95% CI [−0.49, 2.26]). Conclusions An increase in MVPA was associated with a larger decrease in body fat, but neither BMI nor VAT, in non-Latinos compared to Latinos. This suggests that changes in VAT and BMI in response to MVPA may be less influenced by ethnicity than is total body fatness.

show abstract

Abdominal obesity is associated with arterial stiffness in middle-aged adults

Cited by 116 publications

References 42 publications

Arterial Stiffness: Pathophysiological and Genetic Aspects

Arterial Stiffness: Pathophysiological and Genetic Aspects

Pulse wave analysis and diabetes mellitus. A systematic review

Associations between physical activity and BMI, body fatness, and visceral adiposity in overweight or obese Latino and non-Latino adults

Contact Info

Product

Resources

About