Abdominal organ protection strategy for aortic arch aneurysm surgery

Miyamoto, Sadaaki; Takahashi, Shinya; Okahara, Shigeyuki; Takahashi, Hiroyuki; Katayama, Kosuke; Watanabe, Masahiro; Maeda, Kazuki; Go, Seimei; Morita, Shohei; Kurosaki, T.; Herlambang, Bagus; Sueda, Taijiro

doi:10.1177/0267659118768149

Cited by 4 publications

(2 citation statements)

References 28 publications

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“…Three of the patients, who underwent total arch replacement (TAR) under SCP, were perfused with systemic circulation through an 8-mm artificial conduit in the right subclavian artery. During the systemic circulatory arrest for the distal aortic anastomosis, anterograde SCP was applied to the left carotid and left subclavian arteries using the cerebral perfusion lines [29]. With respect to perfusion management, systemic cooling was performed to ensure a target bladder temperature of 34 or 25 • C for TAR during aortic cross-clamping.…”

Section: Proposed Hematocrit-and Temperture-based Viscosity Modelmentioning

confidence: 99%

Online Prediction of Normal Blood Viscosity During Cardiopulmonary Bypass Using Hematocrit- and Temperature-Dependent Model

et al. 2020

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This paper proposes a mathematical model for online prediction of the hematocrit-and temperature-based normal blood viscosity during cardiopulmonary bypass (CPB). Clinical trials were performed using a previously developed continuous blood viscosity monitoring system, and continuous pressure-and flow-based instantaneous viscosity (η e ) data were collected from 40 patients subjected to mild to moderate hypothermic CPB. The hematocrit and blood temperature data corresponding to η e were also acquired. It was found that the blood viscosity−temperature curves for the different hematocrit levels can be well fitted using linear models, with the parameters of the linear model (slopes and intersects) also exhibiting linear relationships with the hematocrit. Based on these relationships, we were able to predict the hematocrit-and temperature-based normal viscosity (η 0 ). To test the prediction accuracy, η 0 was compared with η e using the leave-one-out cross-validation procedure. Furthermore, η 0 and the offlinemeasured viscosity (η), determined using a conventional viscometer, were compared for 20 patients subjected to mildly hypothermic CPB. η 0 and η e -two online blood viscosity monitoring methods based on different principles-showed good agreement (R 2 = 0.74 and p < 0.0001). Moreover, η 0 and η also showed good agreement (R 2 = 0.69 and p < 0.0001). The proposed model is suitable for online prediction of the hematocrit-and temperature-based normal blood viscosity during CPB. The proposed model can function as the core of a future application for investigating the effects of blood viscosity during clinical perfusion management and facilitate detailed online blood viscosity studies.

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Section: Proposed Hematocrit-and Temperture-based Viscosity Modelmentioning

confidence: 99%

Online Prediction of Normal Blood Viscosity During Cardiopulmonary Bypass Using Hematocrit- and Temperature-Dependent Model

et al. 2020

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“…In this issue of Perfusion , Miyamoto and colleagues report their experience of organ protection during aortic arch surgery. 2 My immediate thought while reading the abstract was that renal and hepatic outcomes are bound to be better when you perfuse the distal aorta. Of course, organs will be better protected from injury if they are perfused – it’s another no-brainer!…”

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confidence: 99%