thologists, with this condition and operation, we present the clinical, surgical, and pathological data of our patient; we also review the cases in the literature.
Case reportA 49-year-old man underwent gastric fiberscopy because of a positive result on a fecal occult blood test. He had a 6-year history of HIV infection, which had been controlled with anti-HIV drugs, including indinavir sulfate ethanolate, lamividine, and sanilvudine. On gastric fiberscopy, there was an irregularly shaped, superficially depressed, IIc-type lesion on the anterior wall of the gastric antrum. Histologic examination of the biopsy specimen showed that the lesion was a well differentiated tubular adenocarcinoma of the stomach. Physical examination revealed no palpable lymph nodes, and total colonoscopy disclosed a small adenomatous polyp of the sigmoid colon. Blood data were as follows: red blood cells, 358 ϫ 10 4 /mm 3 , white blood cells, 6000/mm 3 ; lymphocytes, 27.5%; CD 4ϩ cell count, 530/mm 3 ; CD 4ϩ , 31.2%; CD 8ϩ , 42.2%; CD 4ϩ /CD 8ϩ , 0.74; platelets, 16.9 ϫ 10 4 /mm 3 ; total protein, 8.10 g/dl; albumin, 4.58 g/dl; c-reactive protein (CRP), 0.47 mg/dl; and carcinoembryonic antigen (CEA), 1.3 ng/ml. With a diagnosis of early gastric cancer associated with HIV infection, we carried out Billroth I gastrectomy, on October 16, 2000.At operation, we abided strictly by standard precautions for patients with HIV infection. All surgeons and the assistant nurse wore surgical caps, masks, goggles, gowns, two pairs of gloves, and stockings (Fig. 1). Surgical instruments were handed from assistant nurse to operator, and the knife, needles, and blood-contaminated gauzes were placed in a tray by the operator and emptied into a needle-stick prevention box (Sharps Container XX-ST08B; Terumo, Tokyo, Japan) by the third assistant (Fig. 2). With the patient under general Abstract Gastric cancer associated with human immunodeficiency virus (HIV) infection is rare, and mostly results in a poor outcome. We report a patient with HIV infection and early gastric cancer successufully treated by gastrectomy. A 49-year-old man with a 6-year history of HIV infection underwent gastric fiberscopy, and a IIc-type depressed lesion was detected in the gastric antrum. With a diagnosis of early gastric cancer, we abided strictly by standard precautions for patients with HIV infection and carried out Billroth I gastrectomy. Histologic examination revealed that the lesion (which measured 0.9 ϫ ϫ ϫ ϫ ϫ 0.4 cm in size), was well differentiated tubular adenocarcinoma confined to the mucosa. A review of the literature disclosed that this is the first reported case of early gastric cancer associated with HIV infection.