Objective. To explore the application value of the X-ray digital tomographic fusion technique in the diagnosis of urinary system diseases. Methods. 500 patients with suspected urinary diseases in our hospital were examined by three methods: X-ray digital tomographic fusion imaging (DTS), intravenous pyelography (IVP), and abdominal plain film (KUB), and the image quality before and after tomographic fusion was objectively evaluated. The image quality could be divided into three grades: excellent, good, and poor. Results. The image excellent rate of DTS (88%) was higher than that of IVP (27.5%). The sensitivity of DTS in the diagnosis of renal cyst and space occupying of the bladder was higher than that of IVP (
P
<
0.05
). The accuracy rate of DTS in the diagnosis of urinary calculi was 93.33%, higher than 63.3% of KUB (
P
<
0.001
). The accuracy rate of DTS in the diagnosis of ureteral stricture was 90%, higher than 65% of IVP (
P
=
0.03
). The accuracy of DTS in the diagnosis of hydronephrosis was higher than that of IVP and KUB (
P
<
0.05
). Conclusion. In the examination of urinary system-related diseases, high-definition images can be obtained by timely using sectional fusion technology. Compared with conventional IVP, space occupying lesions such as the bladder and kidney can be displayed more clearly with the help of the tomographic fusion technique, which is helpful to improve the possibility of finding lesions and is of great significance in clinical application.