Abdominal septic aortic pseudoaneurysm caused by Campylobacter jejuni infection: Report of a case

Abstract

Campylobacter jejuni infection is one of the most common bacterial causes of acute gastroenteritis worldwide. An extraintestinal manifestation is rare and, to our knowledge, an aortic aneurysm has until now never been documented. We report a case of a 72-year-old patient with a septic aortic pseudoaneurysm caused by C. jejuni infection. Computed tomography and magnetic resonance imaging showed a pseudoaneurysm in the abdominal aorta. The preoperative blood culture indicated a Gram-negative bacillus, which was identified 7 days later as C. jejuni. An aneurysmectomy, extensive debridement, and an in situ graft wrapped with the omentum were done, and the patient was given a 6-week course of antibiotics. Despite readmissions for abdominal infection and Salmonella bacteremia, a graft infection did not develop. In the 3 years since the procedure the patient has shown no signs of a relapse.

Spondylodiscitis and an aortic aneurysm due to Campylobacter coli

“…Ciprofloxacin was prescribed as prolonged antibiotic therapy in an attempt to obtain permanent high concentrations at the infected site. Although a 3 months duration of treatment for abdominal aortic aneurysms infected with Campylobacter has been evocated in two cases [15,16], considering that an endovascular prosthesis had been inserted in an infected site and the risk of relapsing infection, we considered a life-long antibiotic suppressive therapy as reported for other bacteria [17,18]. A prolonged course of ciprofloxacin was then proposed to the patient due to its activity toward foreign body infection due to Gram-negative bacilli, as demonstrated in both experimental and clinical studies [19-22].…”

Infected Abdominal Aortic Aneurysm Caused by <i>Campylobacter Jejuni</i>

“…There is only one previous report in the English literature describing infected AAA caused by C. jejuni . 7 ) In our case, there were no preceding risk factors for an infected aneurysm (such as enteritis, pneumonia, and dental treatment, etc.). The patient was also not on steroids or other immunosuppressive agents, and did not have immunodeficiency.…”

Campylobacterbacteremia: A rare and under-reported event?

“…Such complications have also been reported in patients hospitalized with Campylobacter-related bacteremia and underlying health problems such as Campylobacterrelated meningitis [80,81], hepatitis [82], arthritis [83], abdominal septic aortic pseudoaneurysm [84], peritonitis [85,86], acute pancreatitis [87,88], cellulitis [89,90], pericarditis [91], endocarditis [92] and hemolytic uremic syndrome (HUS) [93]. Again, these reports indicate that Campylobacter is able to efficiently travel through the blood stream in gastroenteritis patients, specifically to tissues or organs that can only be reached via the circulating blood stream.…”