Abdominal splenosis mimicking peritoneal carcinomatosis of ovarian cancer

Alves, Filipe Barros; Rombo, Diogo M.; Veiga, Vera; Correia, Paulo Santos; Salgado, L.; Cunha, Teresa Margarida

doi:10.1016/j.radcr.2022.11.071

Cited by 3 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among all cases of new carcinomatosis-like appearance on CT which received further workup, the positive predictive value (PPV) of pathologically confirmed new peritoneal malignancy was 82%. Many mimics of peritoneal carcinomatosis have been described in the literature, including peritoneal tuberculosis (TB) [9], fibroids [10], peritoneal sarcoid [11], endometriosis [12], actinomycosis [14], and splenosis [13], some of which were found to result in false positive CT findings in our study. The PPV of these mimics will vary based on their respective prevalences in the population.…”

Section: Discussionmentioning

confidence: 66%

ED diagnosis of peritoneal carcinomatosis

Scheinfeld,

Schwartz,

Fink

2024

Emerg Radiol

View full text Add to dashboard Cite

Purpose The goal of our study was to better characterize new CT diagnoses of peritoneal carcinomatosis (PC) in the ED, and to evaluate how to best identify the primary lesion. Prompt identification of the source of the carcinomatosis may allow for the patient to receive early initial care from the correct clinical service. Methods All new CT cases of PC-like appearance identified on CT in the ED from January 2017 through July 2020. Each report and corresponding medical record were manually reviewed. Patient demographics, presence/absence of intravenous contrast, source organ predicted by the radiologist in the CT scan report, pathologic diagnosis, and amount of ascites were tabulated. Chi-tests were used to test the statistical significance of differences between groups. Results Of the 131 CT cases of new PC-like appearance which received workup, 108 cases had pathologically proven PC and 23 cases had no underlying malignancy yielding a positive predictive value for actual PC of 82%. The most common cause of new PC in women was gynecological (66%), and in men was of GI tract origin (57%). Concordance between radiologist prediction and final pathology was higher with intravenous contrast (58%) compared to without contrast (40%); although this difference was not statistically significant (p = 0.19). A moderate or large amount of ascites was found in more than half of GYN primaries and in adenocarcinoma of unknown primary and there was a statistically significant difference in amount of ascites between cancer primaries (p = 0.01). Conclusion A PC-like appearance on CT in the ED will likely be in patients with known malignancy, but of the new cases, there is a high PPV for it to represent new peritoneal carcinomatosis. Gynecological and GI malignancies are the most common cause in women and men, respectively, and this may help in focusing the radiologist’s search pattern. Usage of intravenous contrast may help in identifying a primary lesion, and the presence of high-volume ascites should suggest a GYN primary or adenocarcinoma of unknown primary when there is no other obvious primary lesion.

show abstract

Section: Discussionmentioning

confidence: 66%

ED diagnosis of peritoneal carcinomatosis

Scheinfeld,

Schwartz,

Fink

2024

Emerg Radiol

View full text Add to dashboard Cite

show abstract

Intra-abdominal tumours in a man in his 30s

Voutsadakis

2024

BMJ

View full text Add to dashboard Cite

Complex ovarian masses: Diagnostic processes and outcomes in a clinical case series of benign tumors

Yared,

Barakat,

Mohsen

et al. 2024

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

This case series explores the diagnostic and management complexities of non-malignant ovarian masses, illustrated through three distinct cases: struma ovarii, mature teratoma, and ovarian mass with peritoneal splenosis. The first case details a struma ovarii initially misinterpreted as a potential malignancy due to its complex imaging features, leading to diagnostic uncertainty. The second case involves a mature teratoma, which, despite typical imaging characteristics, presented significant symptoms that necessitated careful clinical management. The third case highlights an ovarian mass with peritoneal splenosis, a condition often mistaken for metastatic disease, underscoring the need for differential diagnosis, particularly in patients with a history of splenic trauma or surgery. These cases emphasize the importance of a comprehensive diagnostic approach that integrates detailed imaging, surgical findings, and histopathological examination to accurately distinguish between benign and malignant ovarian masses and inform appropriate management strategies.

show abstract

Abdominal splenosis mimicking peritoneal carcinomatosis of ovarian cancer

Cited by 3 publications

References 7 publications

ED diagnosis of peritoneal carcinomatosis

ED diagnosis of peritoneal carcinomatosis

Intra-abdominal tumours in a man in his 30s

Complex ovarian masses: Diagnostic processes and outcomes in a clinical case series of benign tumors

Contact Info

Product

Resources

About