Abdominal splenosis with clinical presentation of metastatic neoplastic disease

Ksiądzyna, Dorota

doi:10.5114/pg.2010.18480

Cited by 2 publications

(4 citation statements)

References 11 publications

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“…An unfavorable consequence is the possibility of recurrence of the disease that was the cause of previous splenectomy. On the positive side, this might reduce the risk of severe infections caused by capsular bacteria, including sepsis [ 3 , 4 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…The differential diagnosis is important, because splenosis may mimic serious diseases such as metastatic cancer, lymphoma, primary liver or renal cancer. Accessory spleens, endometriosis, hemangiomas, multiple adenomas, granulomatous diseases, reactive adenopathy or peritoneal mesothelioma should also be taken into account in the differentiation [ 3 , 4 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…A peripheral blood smear may show absence of typical post-splenectomy hematological markers such as Howell–Jolly bodies or siderocytes, an increase in reticulocyte count, or protective pneumococcal antibody levels in an unvaccinated person [ 3 , 4 , 6 , 7 ]. Common imaging tests, such as ultrasound or CT, have a limited diagnostic value in this disorder [ 4 , 7 ]. The gold standard method is radionuclide imaging using Tc-99 m-labeled and heat-damaged erythrocytes [ 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…After the diagnosis has been confirmed, no further treatment is required, except for symptomatic patients [ 7 ]. Surgery is indicated in all patients with symptoms or complications, in case of an uncertain diagnosis and suspected neoplastic process [ 4 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Splenosis mimicking lymphadenopathy

Chorbińska

Krajewski

Sroczyński

et al. 2020

Journal of Surgical Case Reports

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Splenosis is an autotransplantation of splenic tissue following traumatic rupture of the spleen or splenectomy. Generally, splenosis is asymptomatic. Therefore, most cases are incidental findings made during surgery, autopsy or after imaging studies for other purposes. Splenosis is a benign phenomenon, but it often shows similarity to the metastatic process. We present a case of asymptomatic intraperitoneal splenosis occurring in a 57-year-old male, in whom computed tomography urography showed lymphadenopathy suggesting a neoplastic process. A reconnaissance laparotomy was performed, and specimens were taken and sent for histopathological examination. The microscopic image of all the collected lesions corresponded to the normal spleen tissue. Due to an increasing number of traffic accidents, it is worth taking abdominal splenosis into consideration in the differential diagnosis of tumor-like changes, especially in patients with a history of splenic trauma or spleen removal. As a result, unnecessary surgery can be avoided in many cases.

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Section: Discussionmentioning

confidence: 99%