Acute abdomen can be defined as a clinical condition often requires emergency surgical therapy and characterized by severe abdominal pain with tenderness that develops over a short period of time, generally less than 24 hours. There are a variety of conditions that can present clinically with acute abdomen such as: inflammatory, vascular, mechanic, traumatic. In many cases, the clinical presentation is similar, independent of etiology. The radiological imaging plays very important role to determine the need for operative intervention and initiate appropriate therapy. Our aim is to describe the computed tomography findings of the most common conditions of acute abdomen excluding trauma and pediatric or obstetric patients.